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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
A collaborative exercise on cytogenic dosimetry for simulated whole and partial body accidental irradiation
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, Volume 179, No. 2, Year 1987
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Description
An experiment sponsored by the International Atomic Energy Agency was undertaken to compare dose estimation by cytogenetic analysis on aliquots of samples of irradiated blood sent by air to participating laboratories. Accidental acute whole-body irradiations to 0.7 and 2.34 Gy and half-body irradiations to 3.5 Gy were simulated with X- and γ-rays. For the partial irradiations the size of the irradiated fraction and its dose were estimated by the Qdr and contaminated Poisson techniques. Each laboratory's in vitro dose-response data were fitted to the quadratic model by the iteratively reweighted least squares method. Interlaboratory variations in dose-response curves, and in the aberration yields and dose estimates for the simulated accidents were noted. However, in general, most participants consistently obtained results acceptably close to the true values. © 1987.
Authors & Co-Authors
Lloyd, D. C.
United Kingdom, London
Public Health England
Edwards, A. A.
United Kingdom, London
Public Health England
Prosser, J. S.
United Kingdom, London
Public Health England
Barjaktarovic, N.
Croatia, Zagreb
University of Zagreb School of Medicine
Brown, J. K.
Australia, Sydney
Australian Nuclear Science and Technology Organisation
Horvat, D.
Croatia, Zagreb
Institut za Medicinska Istrazivanja I Medicinu Rada
Ismail, Suzan Roushdy
Egypt, Alexandria
Alexandria University
Köteles, G. J.
Hungary, Budapest
National Research Institute for Radiobiology and Radiohygiene Budapest
Almassy, Z.
Hungary, Budapest
National Research Institute for Radiobiology and Radiohygiene Budapest
Krepinsky, A.
Canada, Toronto
Bio-mutatech Inc.
Kucerova, M.
Czech Republic, Prague
Postgraduate Medical Institute
Littlefield, L. G.
United States, Oak Ridge
Orau
Mukherjee, U.
Austria
Institut Für Biologie
Natarajan, A. T.
Netherlands, Leiden
Leids Universitair Medisch Centrum
Sasaki, M. S.
Japan, Kyoto
Kyoto University
Statistics
Citations: 66
Authors: 15
Affiliations: 12
Identifiers
Doi:
10.1016/0027-5107(87)90310-1
ISSN:
00275107
Research Areas
Environmental
Study Approach
Quantitative