Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
The Lancet Regional Health - Europe, Volume 29, Article 100635, Year 2023
Notification
URL copied to clipboard!
Description
Background: The risk factors for recovery from COVID-19 dyspnoea are poorly understood. We investigated determinants of recovery from dyspnoea in adults with COVID-19 and compared these to determinants of recovery from non-COVID-19 dyspnoea. Methods: We used data from two prospective cohort studies: PHOSP-COVID (patients hospitalised between March 2020 and April 2021 with COVID-19) and COVIDENCE UK (community cohort studied over the same time period). PHOSP-COVID data were collected during hospitalisation and at 5-month and 1-year follow-up visits. COVIDENCE UK data were obtained through baseline and monthly online questionnaires. Dyspnoea was measured in both cohorts with the Medical Research Council Dyspnoea Scale. We used multivariable logistic regression to identify determinants associated with a reduction in dyspnoea between 5-month and 1-year follow-up. Findings: We included 990 PHOSP-COVID and 3309 COVIDENCE UK participants. We observed higher odds of improvement between 5-month and 1-year follow-up among PHOSP-COVID participants who were younger (odds ratio 1.02 per year, 95% CI 1.01–1.03), male (1.54, 1.16–2.04), neither obese nor severely obese (1.82, 1.06–3.13 and 4.19, 2.14–8.19, respectively), had no pre-existing anxiety or depression (1.56, 1.09–2.22) or cardiovascular disease (1.33, 1.00–1.79), and shorter hospital admission (1.01 per day, 1.00–1.02). Similar associations were found in those recovering from non-COVID-19 dyspnoea, excluding age (and length of hospital admission). Interpretation: Factors associated with dyspnoea recovery at 1-year post-discharge among patients hospitalised with COVID-19 were similar to those among community controls without COVID-19. Funding: PHOSP-COVID is supported by a grant from the MRC-UK Research and Innovation and the Department of Health and Social Care through the National Institute for Health Research (NIHR) rapid response panel to tackle COVID-19. The views expressed in the publication are those of the author(s) and not necessarily those of the National Health Service (NHS), the NIHR or the Department of Health and Social Care. COVIDENCE UK is supported by the UK Research and Innovation, the National Institute for Health Research, and Barts Charity. The views expressed are those of the authors and not necessarily those of the funders. © 2023 The Author(s)
Authors & Co-Authors
Vivaldi, Giulia
United Kingdom, London
Queen Mary University of London
Daines, Luke
United Kingdom, Edinburgh
The University of Edinburgh
Richardson, Matthew
Unknown Affiliation
Harris, Victoria C.
United Kingdom, Leicester
University Hospitals of Leicester Nhs Trust
Houchen-Wolloff, Linzy
United Kingdom, Wakefield
Nhs England
Pfeffer, Paul E.
United Kingdom, London
Barts Health Nhs Trust
United Kingdom, London
Queen Mary University of London
Hurst, John Robert
United Kingdom, London
University College London
Brown, Jeremy Stuart
United Kingdom, London
University College London
de Soyza, Anthony
United Kingdom, Newcastle
The Newcastle Upon Tyne Hospitals Nhs Foundation Trust
United Kingdom, Newcastle
Newcastle University
Harrison, Ewen M.
United Kingdom, Edinburgh
The University of Edinburgh
Docherty, Annemarie Beth
United Kingdom, Edinburgh
The University of Edinburgh
Lone, Nazir Iftikhar
United Kingdom, Edinburgh
The University of Edinburgh
United Kingdom, Edinburgh
Nhs Lothian
Quint, Jennifer K.
United Kingdom, London
Imperial College London
Chalmers, James D.
United Kingdom, Dundee
University of Dundee
Horsley, Alexander Robert
United Kingdom, Manchester
The University of Manchester
United Kingdom, Manchester
Manchester University Nhs Foundation Trust
Marks, Michael E.
United Kingdom, London
London School of Hygiene & Tropical Medicine
United Kingdom, London
University College London Hospitals Nhs Foundation Trust
United Kingdom, London
University College London
Raman, Betty
United Kingdom, Oxford
University of Oxford
United Kingdom, Oxford
Oxford University Hospitals Nhs Foundation Trust
Heaney, Liam G.
United Kingdom, Belfast
Queen's University Belfast
Wain, Louise V.
United Kingdom, Leicester
University of Leicester
Evans, Rachael Andrea
United Kingdom, Leicester
University Hospitals of Leicester Nhs Trust
Brightling, Christopher Edward
Unknown Affiliation
Martineau, Adrian R.
United Kingdom, London
Queen Mary University of London
United Kingdom, London
Asthma uk
Sheikh, Aziz
United Kingdom, Edinburgh
The University of Edinburgh
United Kingdom, London
Asthma uk
Abel, Kathryn M.
Unknown Affiliation
Adeloye, Davies O.
Unknown Affiliation
Adeyemi, Oluwaseun
Unknown Affiliation
Allan, L. M.
Unknown Affiliation
Allen, Richard James
Unknown Affiliation
Almeida, Paula
Unknown Affiliation
Antoniades, Charalambos A.
Unknown Affiliation
Baillie, John Kenneth
Unknown Affiliation
Bain, Stephen C.
Unknown Affiliation
Baldwin, David R.
Unknown Affiliation
Baldwin, Matthew R.
Unknown Affiliation
Ballard, Clive G.
Unknown Affiliation
Banerjee, Amitava
Unknown Affiliation
Batterham, Rachel Louise
Unknown Affiliation
Baxendale, Helen E.
Unknown Affiliation
Bayes, Hannah Kelly
Unknown Affiliation
Beadsworth, Michael B.J.
Unknown Affiliation
Beckett, Paul A.
Unknown Affiliation
Bell, Robert M.
Unknown Affiliation
Bermperi, Areti
Unknown Affiliation
Bhui, Kamaldeep Singh
Unknown Affiliation
Bisnauthsing, Karen N.
Unknown Affiliation
Bolton, Charlotte E.
Unknown Affiliation
Bramham, Kate
Unknown Affiliation
Breen, Gerome
Unknown Affiliation
Briggs, Andrew M.
Unknown Affiliation
Brown, Julianne S.
Unknown Affiliation
Brown, Michael M.
Unknown Affiliation
Brugha, Traolach Sean
Unknown Affiliation
Brunskill, N. J.
Unknown Affiliation
Burn, David J.
Unknown Affiliation
Burns, Gerard
Unknown Affiliation
Burns, Alistair S.
Unknown Affiliation
Busby, John
Unknown Affiliation
Calder, Philip C.
Unknown Affiliation
Carson, Gail Lindsay
Unknown Affiliation
Casey, Anna L.
Unknown Affiliation
Cassar, Mark Philip
Unknown Affiliation
Chalder, Trudie
Unknown Affiliation
Chalmers, John D.
Unknown Affiliation
Channon, Keith Michael
Unknown Affiliation
Chaudhuri, Nazia
Unknown Affiliation
Chilvers, Edwin R.
Unknown Affiliation
Chinoy, Hector
Unknown Affiliation
Chiribiri, Amedeo
Unknown Affiliation
Chowienczyk, Phil John
Unknown Affiliation
Clohisey, Sara M.R.
Unknown Affiliation
Coleman, Christopher M.
Unknown Affiliation
Connolly, Bronwen A.
Unknown Affiliation
Cooper, D. James
Unknown Affiliation
Coupland, Carol A.C.
Unknown Affiliation
Cullinan, Paul
Unknown Affiliation
Cuthbertson, D. J.
Unknown Affiliation
Dark, Paul M.
Unknown Affiliation
Davies, E. Bethan
Unknown Affiliation
Davies, Melanie J.
Unknown Affiliation
Defres, Sylviane
Unknown Affiliation
Bakerly, Nawar Diar
Unknown Affiliation
Djukanovic, Ratko
Unknown Affiliation
Dong, Tao
Unknown Affiliation
Dormand, Natalie C.
Unknown Affiliation
Easom, Nicholas J.W.
Unknown Affiliation
Edwards, Sarah Louise
Unknown Affiliation
Elmer, Anne
Unknown Affiliation
Evans, David A.
Unknown Affiliation
Felton, Tim W.
Unknown Affiliation
Fisher, Helen L.
Unknown Affiliation
Forton, Daniel M.
Unknown Affiliation
Francis, Susan T.
Unknown Affiliation
Free, Robert C.
Unknown Affiliation
French, N.
Unknown Affiliation
Fuld, Jonathan Paul
Unknown Affiliation
Geddes, John Richard
Unknown Affiliation
George, Jacob
Unknown Affiliation
Gleeson, Fergus V.
Unknown Affiliation
Greenhalf, William
Unknown Affiliation
Greenwood, John Pierre
Unknown Affiliation
Gregory, Rebecca
Unknown Affiliation
Haldar, Pranabashis
Unknown Affiliation
Hardwick, Hayley E.
Unknown Affiliation
Hargadon, Beverley
Unknown Affiliation
Hart, Nicholas
Unknown Affiliation
Heeney, Jonathan
Unknown Affiliation
Heightman, Melissa J.
Unknown Affiliation
Heller, Simon R.
Unknown Affiliation
Ho, Ling Pei
Unknown Affiliation
Hosseini, Akram A.
Unknown Affiliation
Hotopf, Matthew Hugo
Unknown Affiliation
Howell, Alice
Unknown Affiliation
Hughes, Rachael A.
Unknown Affiliation
Huneke, Nathan T.M.
Unknown Affiliation
Hussell, Tracy
Unknown Affiliation
Jackson, Thomas A.
Unknown Affiliation
Jacob, Joseph
Unknown Affiliation
Johnson, Simon R.
Unknown Affiliation
Jolley, Caroline J.
Unknown Affiliation
Jones, Laura L.
Unknown Affiliation
Jones, Mark G.
Unknown Affiliation
Jose, Sherly
Unknown Affiliation
Kamwa, Vicky
Unknown Affiliation
Kerr, Steven
Unknown Affiliation
Khunti, Kamlesh K.
Unknown Affiliation
Klenerman, Paul
Unknown Affiliation
Knight, Sean Blandin
Unknown Affiliation
Kon, Onn Minn
Unknown Affiliation
Kurupati, Prathiba
Unknown Affiliation
Langenberg, Claudia C.
Unknown Affiliation
Lasserson, Daniel S.
Unknown Affiliation
Lewis, David A.
Unknown Affiliation
Lightstone, Liz
Unknown Affiliation
Lingford-Hughes, Anne R.
Unknown Affiliation
Lipman, Marc CI
Unknown Affiliation
Logan, Sarah A.E.
Unknown Affiliation
MacGowan, Guy Andrew
Unknown Affiliation
Malim, Michael H.
Unknown Affiliation
Mandal, Swapna
Unknown Affiliation
Mangion, Kenneth
Unknown Affiliation
Manisty, Charlotte H.
Unknown Affiliation
March, Katherine
Unknown Affiliation
Maskell, Nick Anthony
Unknown Affiliation
McArdle, Patrick F.
Unknown Affiliation
McGarvey, Lorcan Patrick Augustine
Unknown Affiliation
McNarry, Melitta A.
Unknown Affiliation
McQueen, Alison
Unknown Affiliation
McShane, Helen
Unknown Affiliation
Mehta, Puja
Unknown Affiliation
Meiring, James E.
Unknown Affiliation
Mills, Nicholas Linton
Unknown Affiliation
Misra, S.
Unknown Affiliation
Molyneaux, Philip L.
Unknown Affiliation
Moss, Alastair James
Unknown Affiliation
Moss, Paul A.H.
Unknown Affiliation
Mukaetova-Ladinska, Elizabeta Blagoja
Unknown Affiliation
Neubauer, Stefan
Unknown Affiliation
Nicholson, Timothy R.
Unknown Affiliation
O'Brien, Caitlin
Unknown Affiliation
O'Regan, Declan P.
Unknown Affiliation
Ogg, Graham Stuart
Unknown Affiliation
Openshaw, Peter J.M.
Unknown Affiliation
Ostermann, Marlies Elizabeth
Unknown Affiliation
Paddick, Stella Maria
Unknown Affiliation
Papineni, Padmasayee
Unknown Affiliation
Pareek, Manish
Unknown Affiliation
Parekh, Dhruv
Unknown Affiliation
Parfrey, Helen
Unknown Affiliation
Pariante, Carmine M.
Unknown Affiliation
Pavlides, Michael
Unknown Affiliation
Pearl, John E.
Unknown Affiliation
Peckham, Daniel Gavin
Unknown Affiliation
Peng, Yanchun
Unknown Affiliation
Peto, Timothy E.A.
Unknown Affiliation
Petousi, Nayia
Unknown Affiliation
Pius, Riinu
Unknown Affiliation
Plein, Sven
Unknown Affiliation
Price, Anna
Unknown Affiliation
Rahman, Najib Mahboob
Unknown Affiliation
Ralser, Markus
Unknown Affiliation
Reddy, Raja Vongala
Unknown Affiliation
Ribeiro, Carla G.
Unknown Affiliation
Rivera-Ortega, Pilar
Unknown Affiliation
Roberts, John Keith
Unknown Affiliation
Robinson, Leanne J.
Unknown Affiliation
Rowland-Jones, Sarah Louise
Unknown Affiliation
Rudan, Igor
Unknown Affiliation
Russell, Richard E.K.
Unknown Affiliation
Samani, Nilesh J.
Unknown Affiliation
Sapey, Elizabeth
Unknown Affiliation
Sattar, Naveed
Unknown Affiliation
Saunders, Kate E. A.
Unknown Affiliation
Sayer, A. A.
Unknown Affiliation
Scott, Janet T.
Unknown Affiliation
Semple, Malcolm Gracie
Unknown Affiliation
Shah, Karishma
Unknown Affiliation
Shankar-Hari, Manu
Unknown Affiliation
Shaw, Karen L.
Unknown Affiliation
Sheikh, Aadil Ahmad
Unknown Affiliation
Sigfrid, Louise A.
Unknown Affiliation
Smith, Susan M.
Unknown Affiliation
Soares, Marcio
Unknown Affiliation
Steiner, Michael C.
Unknown Affiliation
Stewart, Iain D.
Unknown Affiliation
Sudlow, Cathie L.M.
Unknown Affiliation
Summers, Charlotte
Unknown Affiliation
Talbot, Nick P.
Unknown Affiliation
Thomas, Sarah R.
Unknown Affiliation
Thompson, A. A.Roger
Unknown Affiliation
Thwaites, Ryan S.
Unknown Affiliation
Toshner, Mark R.
Unknown Affiliation
Touyz, Rhian M.
Unknown Affiliation
Turtle, Lance C.W.
Unknown Affiliation
Valabhji, Jonathan
Unknown Affiliation
Wainwright, Tania
Unknown Affiliation
Wall, Emma C.B.
Unknown Affiliation
Welch, Carly
Unknown Affiliation
Welch, Hugh
Unknown Affiliation
Wessely, Simon Charles
Unknown Affiliation
Wild, Jim M.
Unknown Affiliation
Williams, Nicola C.
Unknown Affiliation
Wilson, Deborah A.
Unknown Affiliation
Wootton, Dan G.
Unknown Affiliation
Wormleighton, Joanne V.
Unknown Affiliation
Worsley, Jieniean
Unknown Affiliation
Wright, Shaney
Unknown Affiliation
Yousuf, Ahmed J.
Unknown Affiliation
Zheng, Bang
Unknown Affiliation
Statistics
Citations: 1
Authors: 228
Affiliations: 21
Identifiers
Doi:
10.1016/j.lanepe.2023.100635
ISSN:
26667762
Research Areas
Covid
Health System And Policy
Mental Health
Noncommunicable Diseases
Study Design
Cohort Study
Case-Control Study
Participants Gender
Male