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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
International cooperative study on the relationship between dietary factors and blood pressure: A report from the cardiovascular diseases and alimentary comparison (CARDIAC) study
Journal of Cardiovascular Pharmacology, Volume 16, Year 1990
Notification
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Description
To investigate the epidemiological relationship of dietary factors to blood pressure (BP) and major cardiovascular diseases, we carried out the International Cooperative Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study, which so far involves 45 centers in 20 countries. From each population, 100 men and 100 women aged 50-54 years were randomly selected for BP measurement, 24-h urine collection, and blood test. Various biological markers of diets from urine and blood were analyzed centrally in the Izumo CARDIAC center. In within-center multiple regression analyses, body mass index (BMI) was strongly positively and independently associated with BP. Urine magnesium (Mg) excretion was negatively and independently associated with BP. In cross-center simple regression analyses, systolic and diastolic BP showed significant correlations with BMI (p < 0.01) and 24-h urinary sodium (Na) excretion p < 0.005) in men and significant inverse correlations with urinary 3-methylhistidine (3-MH) divided by creatinine (p < 0.01 and p < 0.005, respectively) in men, and were inversely correlated with urinary Mg in women (p < 0.05). Therefore, Na and BMI adversely affect BP, whereas animal protein and Mg intakes may have beneficial influence on BP. © 1990 Raven Press, Ltd., New York.
Authors & Co-Authors
Yamori, Yukio
Japan, Matsue
Shimane University
Nara, Yasuo
Japan, Matsue
Shimane University
Mizushima, S.
Japan, Matsue
Shimane University
Mano, M.
Japan, Matsue
Shimane University
Sawamura, M.
Japan, Matsue
Shimane University
Kihara, Masahiro
Japan, Matsue
Shimane University
Hone, R.
Japan, Matsue
Shimane University
Beilin, Lawerence Joseph
Unknown Affiliation
Hobbs, Michael S.T.
Unknown Affiliation
Jamrozik, Konrad D.
Unknown Affiliation
Amery, A.
Unknown Affiliation
DeBacker, G.
Unknown Affiliation
DeBacker, G.
Unknown Affiliation
Nicolov, N.
Unknown Affiliation
Tomov, I.
Unknown Affiliation
Moriguchi, Yukio
Unknown Affiliation
Chockalin-Gam, A.
Unknown Affiliation
Fodor, Jiri George
Unknown Affiliation
He, B. X.
Unknown Affiliation
Huang, Z. D.
Unknown Affiliation
Liu, L. S.
Unknown Affiliation
Sun, S. F.
Unknown Affiliation
Zhang, H. X.
Unknown Affiliation
Davalos, D.
Unknown Affiliation
De Pozo, V.
Ecuador
Vilcabamba
Tuomilehto, Jaakko O.I.
Unknown Affiliation
Ioanidis, A.
Israel
Tel Hashomar
Cesana, Giancarlo
Unknown Affiliation
Ogoshi, T.
Japan
Ohda
Kagamimori, Sadanobu
Unknown Affiliation
Kanazawa, T.
Unknown Affiliation
Kodama, S.
Unknown Affiliation
Mimura, G.
Unknown Affiliation
To-Shima, H.
Unknown Affiliation
Yamakido, M.
Unknown Affiliation
Simpson, F. O.
Unknown Affiliation
Carrageta, Manuel Oliveira
Unknown Affiliation
Fernandez-Cruz, A.
Unknown Affiliation
Wilhelmsen, Lars W.
Unknown Affiliation
Mtabaji, Jacob Phillip
Tanzania, Bagamoyo
Dar es Salaam
Birt, Christopher A.
United Kingdom, Isle of Lewis
Stornoway
Evans, Alun E.
United Kingdom, Belfast
Belfast
Langford, H. G.
Unknown Affiliation
Oganov, Rafael G.
Unknown Affiliation
Dalakish-Villi, S. M.
Russian Federation
Caucasus
Ya-Mori, Y.
Unknown Affiliation
Horic, R.
Unknown Affiliation
Nara, Y.
Unknown Affiliation
Sawamura, M.
Unknown Affiliation
Mano, M.
Unknown Affiliation
Mizushima, S.
Unknown Affiliation
Strasser, T.
Unknown Affiliation
Ue-Mura, K.
Unknown Affiliation
Statistics
Citations: 71
Authors: 53
Affiliations: 8
Identifiers
Doi:
10.1097/00005344-199000168-00018
ISSN:
01602446
e-ISSN:
15334023
Research Areas
Noncommunicable Diseases
Study Design
Cross Sectional Study
Participants Gender
Male
Female