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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
environmental science
Response of Aedes aegypti (diptera: culicidae) larvae to three xenobiotic exposures: Larval tolerance and detoxifying enzyme activities
Environmental Toxicology and Chemistry, Volume 25, No. 2, Year 2006
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Description
The ability of mosquito larvae to tolerate toxic compounds (temephos, Bacillus thuringiensis var. israelensis, toxic vegetable leaf litter) was examined on a laboratory larval strain of Aedes aegypti L. Bioassays and detoxifying enzyme activity measurements were performed to compare tolerance/resistance capacities. The possibility of a functional plasticity of detoxifying equipment was investigated through experimental determination of the inductive effect of each xenobiotic within a given generation. In the same way, the selective effect of a toxic leaf litter was also investigated along successive generations. Results revealed that differential cytochrome P450 monooxygenase, esterase, and glutathione S-transferase activity levels correlated with the bioassay results. Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities. © 2006 SETAC.
Authors & Co-Authors
Boyer, Sebastien
France, Saint Martin D'heres
Université Grenoble Alpes
David, Jean Philippe
United Kingdom, Liverpool
Liverpool School of Tropical Medicine
Lempérière, Guy
France, Saint Martin D'heres
Université Grenoble Alpes
Ravanel, Patrick
France, Saint Martin D'heres
Université Grenoble Alpes
Statistics
Citations: 44
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1897/05-267R2.1
ISSN:
07307268
Research Areas
Environmental
Study Design
Exploratory Study
Study Approach
Qualitative