Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Esophageal and gastric malignancies after bariatric surgery: a retrospective global study
Surgery for Obesity and Related Diseases, Volume 18, No. 4, Year 2022
Notification
URL copied to clipboard!
Description
Background: Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized. Objective: To characterize EG malignancies after bariatric procedures. Setting: University Hospital, United Kingdom. Methods: We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition. Results: This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period. Conclusion: The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition. © 2021 American Society for Bariatric Surgery
Authors & Co-Authors
Parmar, Chetan D.
United Kingdom, London
Whittington Health Nhs Trust
Zakeri, Roxanna
United Kingdom, London
Whittington Health Nhs Trust
United Kingdom, London
University College London
Abouelazayem, Mohamed
United Kingdom, London
St George's University Hospitals Nhs Foundation Trust
Aminian, Ali
United States, Cleveland
Cleveland Clinic Foundation
Mahawar, Kamal K.
United Kingdom, Sunderland
South Tyneside and Sunderland Nhs Foundation Trust
Carbajo Caballero, Miguel Ángel
Unknown Affiliation
Kow, Lillian
Unknown Affiliation
Gananadha, Sivakumar
Unknown Affiliation
Felsenreich, Daniel Moritz
Unknown Affiliation
Prager, G. W.
Unknown Affiliation
Matthys, Christophe
Unknown Affiliation
Himpens, Jacques M.
Unknown Affiliation
Focquet, Marc A.M.R.M.
Unknown Affiliation
Ramos, Almino Cardoso
Unknown Affiliation
Andalib, Amin
Unknown Affiliation
Yang, Wah
Unknown Affiliation
Hamed, Hosam
Unknown Affiliation
Liagre, Arnaud
Unknown Affiliation
Genser, Laurent
Unknown Affiliation
Skalli, Mehdi El
Unknown Affiliation
Nedelcu, Marius
Unknown Affiliation
Kassir, Radwan
Unknown Affiliation
Stier, Christine
Unknown Affiliation
Kermansaravi, Mohammad
Unknown Affiliation
Raziel, Asnat
Unknown Affiliation
Sakran, Nasser
Unknown Affiliation
Musella, Mario
Unknown Affiliation
Seki, Yousuke
Unknown Affiliation
Kalinowski, Piotr
Unknown Affiliation
Al-Bahrani, Ahmed Z.
Unknown Affiliation
Al-Zoubi, Moh'D Belal
Unknown Affiliation
Tejedor-Tejada, Javier
Unknown Affiliation
Cuadrado-Ayuso, Marta Bailón
Unknown Affiliation
Kroh, Matthew D.
Unknown Affiliation
Kamocka, Anna
Unknown Affiliation
Sgromo, Bruno
Unknown Affiliation
Gopinath, Bussa R.
Unknown Affiliation
Pournaras, Dimitri J.
Unknown Affiliation
Underwood, Tim James
Unknown Affiliation
Griffiths, Ewen A.
Unknown Affiliation
Wadley, Martin Stuart
Unknown Affiliation
Singhal, Rishi
Unknown Affiliation
Preston, Shaun R.
Unknown Affiliation
Robinson, Steven John
Unknown Affiliation
Adamo, Marco
Unknown Affiliation
Gossage, James A.
Unknown Affiliation
Statistics
Citations: 9
Authors: 46
Affiliations: 9
Identifiers
Doi:
10.1016/j.soard.2021.11.024
ISSN:
15507289
Research Areas
Cancer
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Female