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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
MHC-dependent survival in a wild population: Evidence for hidden genetic benefits gained through extra-pair fertilizations
Molecular Ecology, Volume 19, No. 16, Year 2010
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Description
Females should prefer to be fertilized by males that increase the genetic quality of their offspring. In vertebrates, genes of the major histocompatibility complex (MHC) play a key role in the acquired immune response and have been shown to affect mating preferences. They are therefore important candidates for the link between mate choice and indirect genetic benefits. Higher MHC diversity may be advantageous because this allows a wider range of pathogens to be detected and combated. Furthermore, individuals harbouring rare MHC alleles might better resist pathogen variants that have evolved to evade common MHC alleles. In the Seychelles warbler, females paired with low MHC-diversity males elevate the MHC diversity of their offspring to levels comparable to the population mean by gaining extra-pair fertilizations. Here, we investigate whether increased MHC diversity results in higher life expectancy and whether there are any additional benefits of extra-pair fertilizations. Our 10-year study found a positive association between MHC diversity and juvenile survival, but no additional survival advantage of extra-pair fertilizations. In addition, offspring with a specific allele (Ase-ua4) had a fivefold longer life expectancy than offspring without this allele. Consequently, the interacting effects of sexual selection and pathogen-mediated viability selection appear to be important for maintaining MHC variation in the Seychelles warbler. Our study supports the prediction that MHC-dependent extra-pair fertilizations result in genetic benefits for offspring in natural populations. However, such genetic benefits might be hidden and not necessarily apparent in the widely used fitness comparison of extra- and within-pair offspring. © 2010 Blackwell Publishing Ltd.
Authors & Co-Authors
Brouwer, Lyanne
United Kingdom, Norwich
University of East Anglia
Norway, Trondheim
Norges Teknisk-naturvitenskapelige Universitet
Australia, Canberra
Anu Research School of Biology
Barr, Iain R.
United Kingdom, Norwich
University of East Anglia
Van De Pol, Martijn
Australia, Canberra
Anu Research School of Biology
Burke, Terry A.
United Kingdom, Sheffield
The University of Sheffield
Komdeur, Jan
Netherlands, Groningen
Rijksuniversiteit Groningen
Richardson, David S.
United Kingdom, Norwich
University of East Anglia
Seychelles, Mahe
Nature Seychelles
Statistics
Citations: 121
Authors: 6
Affiliations: 6
Identifiers
Doi:
10.1111/j.1365-294X.2010.04750.x
ISSN:
09621083
e-ISSN:
1365294X
Research Areas
Genetics And Genomics
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Study Locations
Seychelles
Participants Gender
Female