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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Epidemiologic and clinical aspects of a Rift Valley fever outbreak in humans in Tanzania, 2007
American Journal of Tropical Medicine and Hygiene, Volume 83, No. 2 SUPPL., Year 2010
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Description
In January 2007, an outbreak of Rift Valley fever (RVF) was detected among humans in northern Tanzania districts. By the end of the outbreak in June, 2007, 511 suspect RVF cases had been recorded from 10 of the 21 regions of Tanzania, with laboratory confirmation of 186 cases and another 123 probable cases. All confirmed RVF cases were located in the north-central and southern regions of the country, with an eventual fatality rate of 28.2% (N = 144). All suspected cases had fever; 89% had encephalopathy, 10% hemorrhage, and 3% retinopathy. A total of 169 (55%) of the 309 confirmed or probable cases were also positive for malaria as detected by peripheral blood smear. In a cohort of 20 RVF cases with known outcome that were also positive for human immunodeficiency virus, 15 (75%) died. Contact with sick animals and animal products, including blood, meat, and milk, were identified as major risk factors of acquiring RVF. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Mohamed, Mohamed Ally
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Mosha, Fausta Shakiwa
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Mghamba, Janneth Maridadi
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Zaki, Sherif R.
United States, Atlanta
Centers for Disease Control and Prevention
Shieh, Wun Ju
United States, Atlanta
Centers for Disease Control and Prevention
Pawȩska, Janusz Tadeusz
Unknown Affiliation
Omulo, Sylvia
Kenya, Kisumu
Centers for Disease Control and Prevention, Kenya
Gikundi, Solomon
Kenya, Kisumu
Centers for Disease Control and Prevention, Kenya
Mmbuji, Peter K.
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Bloland, Peter Brian
United States, Atlanta
Centers for Disease Control and Prevention
Zeidner, Nordin S.
United States, Atlanta
National Center for Emerging and Zoonotic Infectious Diseases
Kalinga, Raphael
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Breiman, Robert F.
Kenya, Kisumu
Centers for Disease Control and Prevention, Kenya
Njenga, Moses Kariuki
Kenya, Kisumu
Centers for Disease Control and Prevention, Kenya
Statistics
Citations: 148
Authors: 14
Affiliations: 4
Identifiers
Doi:
10.4269/ajtmh.2010.09-0318
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cohort Study
Study Locations
Tanzania