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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Urban malaria in the Sahel: Prevalence and seasonality of presumptive malaria and parasitaemia at primary care level in Chad
Tropical Medicine and International Health, Volume 11, No. 2, Year 2006
Notification
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Description
OBJECTIVE: To assess malaria prevalence rates and seasonal patterns among clinically diagnosed malaria cases at the level of primary care facilities in an urban Sahelian setting. Screening all patients consulting two private and two governmental providers on a randomly selected weekday over a period of 9 months. Patients with presumptive malaria underwent a blood test. RESULTS: Of 1658 patients included in the survey, 47% were clinically diagnosed and treated as malaria cases. Malaria was more often diagnosed by private providers. There were no clear seasonal patterns in presumptive malaria. A 30% of clinically diagnosed cases were positive for Plasmodium (all falciparum) by thick film examination. Thus, false positive cases constituted more than 70% of the clinically diagnosed malaria cases. The highest positive prevalence rates were found at the end and shortly after the rainy season (44%-47%) and the lowest during the dry season (2%). CONCLUSIONS: Clinical diagnosis of malaria has a very low positive predicted value in this low endemicity urban setting, and its low specificity leads to inappropriate care for a large proportion of patients. This has a major impact on economic costs for health services and households. In the Sahel, systematic use of microscopy-based diagnosis and/or rapid diagnostic tests should be considered to appropriately manage malaria and non-malaria cases. © 2006 Blackwell Publishing Ltd.
Authors & Co-Authors
Othnigué, Nadjitolnan
Chad, N'djamena
Ministry of Public Health
Chad
Centre de Support en Santé Internationale
Wyss, Kaspar
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Tanner, Marcel
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Genton, Blaise
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Statistics
Citations: 31
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1111/j.1365-3156.2005.01551.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Chad