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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Impact of obesity on surgical outcomes post-pancreaticoduodenectomy: A case-control study
International Journal of Surgery, Volume 12, No. 5, Year 2014
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Description
Background: Obesity is a growing worldwide epidemic. There is association between obesity and pancreatic cancer risk. However, the impact of obesity on the outcome of pancreatoduodenectomy (PD) is controversial. The aim of this study was to elucidate effect of obesity on surgical outcomes of PD. Study design: A case-control study. Patient and methods: We retrospectively studied all patients who underwent PD in our center between January 2000 and June 2012. Patients were divided into two groups; Group A (patients with BMI <25) and Group B (patients with BMI>25). Preoperative demographic data, intraoperative data, and postoperative details were collected. Results: Only 112/471 patients (25.9%) had BMI>25. The median intraoperative blood loss was more in overweight patients (P=0.06). The median surgical time in group B was significantly longer than that in group A (P=0.003). The overall incidence of complications was higher in the overweight group (P=0.001). The severity of complications was also higher in the overweight group (P=0.0001). Postoperative pancreatic fistula (POPF) (P=0.0001) and hospital mortality (P=0.001) were significantly higher in overweight patients. Oral intake was significantly delayed in overweight patients in comparison to normal weight group (P=0.02). Postoperative stay was significantly longer in overweight patients (P=0.0001). Conclusion: PD is associated with an increased risk of postoperative morbidity in overweight patient. Overweight patients must not be precluded from undergoing PD. However, operative techniques and pharmacological prophylaxis to decrease POPF should be considered in overweight patients. © 2014 Surgical Associates Ltd.
Authors & Co-Authors
El Nakeeb, Ayman M.
Egypt, Mansoura
Gastrointestinal Surgery Center
Hamed, Hosam
Egypt, Mansoura
Gastrointestinal Surgery Center
Shehta, Ahmed
Egypt, Mansoura
Gastrointestinal Surgery Center
Askr, Waleed
Egypt, Mansoura
Gastrointestinal Surgery Center
El-Dosoky, Mohamed E.
Egypt, Mansoura
Gastrointestinal Surgery Center
Said, Rami
Egypt, Mansoura
Gastrointestinal Surgery Center
Abdallah, Talaat
Egypt, Mansoura
Gastrointestinal Surgery Center
Statistics
Citations: 31
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1016/j.ijsu.2014.01.017
ISSN:
17439191
e-ISSN:
17439159
Research Areas
Cancer
Health System And Policy
Noncommunicable Diseases
Study Design
Cohort Study
Case-Control Study