Improved Diagnosis of childhood tuberculous meningitis using more than one nucleic acid amplification test
International Journal of Tuberculosis and Lung Disease, Volume 19, No. 1, Year 2015
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METHODS: We assessed the diagnostic accuracy of the GenoType® MTBDRplus and Xpert® MTB/RIF assays on CSF collected from paediatric meningitis suspects prospectively enrolled at Tygerberg Hospital, Cape Town, South Africa. Fluorescent auramine-O microscopy, liquid culture for Mycobacterium tuberculosis, GenoType and Xpert assays were performed on all CSF samples.