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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Staged abdominal closure after small bowel or multivisceral transplantation
Pediatric Transplantation, Volume 16, No. 1, Year 2012
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Description
Following paediatric SBMT, size discrepancy between the recipient's abdomen and the graft may lead to ACS, graft dysfunction, and death. We report our experience with SAC in these patients. Between 04/1993 and 03/2009, 57 children underwent 62 SBMTs. When abdominal wall tension seemed excessive for safe PAC, SAC was performed, using a Silastic Â∞ sheet and a vacuum occlusive dressing. Transplantations with SAC (23 combined liver and small bowel [CLB]) were compared with those with PAC [14 ISB and 25 CLB]. Indications for transplantation, preoperative status (after stratification for ISB/CLB transplants), age at transplantation, donor-to-recipient weight ratio, reduction in bowel and/or liver, and incidence of wound complications were not different in both groups. Post-operative intubation, stay in intensive care unit, and hospital stay were prolonged after SAC. Two deaths were related to ACS after PAC, none after SAC. Since 2000, one-yr patient survival is 73% after ISB transplantation and 57% vs. 75% after CLB transplantation with PAC vs. SAC, respectively (NS). SAC safely reduces severe ACS after paediatric SBMT and can be combined with graft reduction for transplantation of small recipients. © 2011 John Wiley & Sons A/S.
Authors & Co-Authors
Sharif, Khalid
United Kingdom, Birmingham
Birmingham Children's Hospital
Lloyd, Carla
United Kingdom, Birmingham
Birmingham Children's Hospital
Gupte, Girish L.
United Kingdom, Birmingham
Birmingham Children's Hospital
Kelly, Deirdre Anne K.
United Kingdom, Birmingham
Birmingham Children's Hospital
De Ville Goyet, Jean
United Kingdom, Birmingham
Birmingham Children's Hospital
Millar, Allistair John Ward
United Kingdom, Birmingham
Birmingham Children's Hospital
Mirza, Darius Feroze
United Kingdom, Birmingham
Birmingham Children's Hospital
Statistics
Citations: 30
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1111/j.1399-3046.2011.01597.x
ISSN:
13993046
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Cohort Study