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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Assessing the role of the non-pneumatic anti-shock garment in reducing mortality from postpartum hemorrhage in Nigeria
Gynecologic and Obstetric Investigation, Volume 71, No. 1, Year 2011
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Description
Background/Aims: Postpartum hemorrhage (PPH) is the leading cause of maternal mortality. The non-pneumatic anti-shock garment (NASG), a first-aid lower-body pressure device, may decrease mortality. Methods: This pre-intervention/NASG study of 288 women was conducted in four referral facilities in Nigeria, 2004-2008. Entry criteria: women with PPH due to uterine atony, retained placenta, ruptured uterus, vaginal or cervical lacerations or placenta accreta with estimated blood loss of ≥750 ml and one clinical sign of shock. Differences in demographics, conditions on study entry, treatment and outcomes were examined. t tests and relative risks with 95% confidence intervals were calculated for primary outcomes - measured blood loss and mortality. Multiple logistic regression analysis was performed to examine independent association of the NASG with mortality. Results: Mean measured blood loss decreased by 80% between phases. Women experienced 350 ml of median blood loss after study entry in the pre-intervention and 50 ml in the NASG phase (p < 0.0001). Mortality decreased from 18% pre-intervention to 6% in the NASG phase (RR = 0.31, 95% CI 0.15-0.64, p = 0.0007). In a multiple logistic regression model, the NASG was associated with reduced mortality (odds ratio 0.30; 95% CI 0.13-0.68, p = 0.004). Conclusion: The NASG shows promise for reducing mortality from PPH in referral facilities in Nigeria. Copyright © 2010 S. Karger AG, Basel.
Authors & Co-Authors
Ojengbede, Oladosu Akanbi
Nigeria, Ibadan
University College Hospital, Ibadan
Morhason-Bello, Imran Oludare
Nigeria, Ibadan
University College Hospital, Ibadan
Galadanci, Hadiza Shehu
Nigeria, Kano
Aminu Kano Teaching Hospital
Brody, Carinne Meyer
United States, San Francisco
University of California, San Francisco
Nsima, David
Nigeria
Katsina General Hospital
Camlin, Carol S.
United States, San Francisco
University of California, San Francisco
Butrick, Elizabeth A.
United States, San Francisco
University of California, San Francisco
Miller, Suellen P.
United States, San Francisco
University of California, San Francisco
Statistics
Citations: 31
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1159/000316053
ISSN:
03787346
Research Areas
Maternal And Child Health
Violence And Injury
Study Design
Randomised Control Trial
Case-Control Study
Study Approach
Quantitative
Study Locations
Nigeria
Participants Gender
Female