Publication Details

AFRICAN RESEARCH NEXUS

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medicine

Glucose-6-phosphate dehydrogenase status and risk of hemolysis in Plasmodium falciparum-infected African children receiving single-dose primaquine

Antimicrobial Agents and Chemotherapy, Volume 58, No. 8, Year 2014

Glucose-6-phosphate dehydrogenase (G6PD) enzyme function and genotype were determined in Ugandan children with uncomplicated falciparum malaria enrolled in a primaquine trial after exclusion of severe G6PD deficiency by fluorescent spot test. G6PD A-heterozygotes and hemizygotes/homozygotes experienced dose-dependent lower hemoglobin concentrations after treatment. No severe anemia was observed. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Statistics
Citations: 32
Authors: 10
Affiliations: 5
Identifiers
Doi: 10.1128/AAC.02889-14
ISSN: 00664804
e-ISSN: 10986596
Research Areas
Genetics And Genomics
Infectious Diseases
Maternal And Child Health

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