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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The effects of iron and/or zinc supplementation on maternal reports of sleep in infants from Nepal and Zanzibar
Journal of Developmental and Behavioral Pediatrics, Volume 30, No. 2, Year 2009
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Description
BACKGROUND: There is some evidence that sleep patterns may be affected by iron deficiency anemia but the role of iron in sleep has not been tested in a randomized iron supplementation trial. OBJECTIVE: We investigated the effect of iron supplementation on maternal reports of sleep in infants in 2 randomized, placebo-controlled trials from Pemba Island, Zanzibar, and Nepal. DESIGN: In both studies, which had parallel designs and were carried out in years 2002 to 2003, infants received iron-folic acid with or without zinc daily for 12 months, and assessments of development were made every 3 months for the duration of the study. Eight hundred seventy-seven Pemban (12.5 ± 4.0 months old) and 567 Nepali (10.8 ± 4.0 months) infants participated. Maternal reports of sleep patterns (napping frequency and duration, nighttime sleep duration, frequency of night waking) were collected. RESULTS: Mean Hb concentration was 9.2 ± 1.1 for Pemban and 10.1 ± 1.2 g/dL for Nepali infants. Approximately, one-third of the children were stunted. Supplemental iron was consistently associated with longer night and total sleep duration. The effects of zinc supplementation also included longer sleep duration. CONCLUSIONS: Micronutrient supplementation in infants at high risk for iron deficiency and iron deficiency anemia was related to increased night sleep duration and less night waking. © 2009 Lippincott Williams & Wilkins, Inc.
Authors & Co-Authors
Kordas, Katarzyna
United States, University Park
Pennsylvania State University
Siegel, Emily H.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Olney, Deanna K.
United States, Davis
University of California, Davis
Katz, Joanne D.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Tielsch, James M.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Kariger, Patricia K.
United States, Ithaca
Cornell University
Khalfan, Sabra S.
Tanzania, Mkokotoni, Zanzibar
Public Health Laboratory-ivo de Carneri
LeClerq, Steven C.
Nepal, Kathmandu
Nepal Nutrition Intervention Project-sarlahi
Khatry, Subarna K.
Nepal, Kathmandu
Nepal Nutrition Intervention Project-sarlahi
Stoltzfus, Rebecca Joyce
United States, Ithaca
Cornell University
Statistics
Citations: 52
Authors: 10
Affiliations: 6
Identifiers
Doi:
10.1097/DBP.0b013e31819e6a48
ISSN:
0196206X
Research Areas
Maternal And Child Health