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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Temporal Trends and Outcomes of Transcatheter Mitral Valve Repair and Surgical Mitral Valve Intervention
Cardiovascular Revascularization Medicine, Volume 21, No. 12, Year 2020
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Description
Background: There is a paucity of data regarding the contemporary changes in the uptake and outcomes of transcatheter mitral valve repair (TMVR) and surgical mitral valve repair/replacement (SMVR). Methods: We queried the NIS database (2012–2016) to identify hospitalizations for TMVR and SMVR. We reported the temporal trends for uptake of TMVR and SMVR and their in-hospital outcomes. Results: The analysis included 77,645 hospitalizations: 8760 (11.3%) for TMVR and 68,885 (88.7%) for SMVR. Those undergoing TMVR were older and had a higher prevalence of comorbidities, but shorter length of stay (5.5 ± 8.8 vs. 14.3 ± 13.8, p < 0.001) compared with SMVR. There was a marked increase in the number of TMVRs over time (from 420 in 2012 to 3850 in 2016; +917%; Ptrend = 0.008) but a modest increase in the number of SMVRs (+117%; Ptrend = 0.02). Overall, TMVR was associated with low in-hospital mortality (2%) and favorable safety profile. After adjusting for clinical and hospital variables, there were non-significant trends towards lower adjusted mortality among TMVR and SMVR (Ptrend = 0.16 and Ptrend = 0.13, respectively). Notably, among TMVR patients, female sex was associated with lower in-hospital mortality while CKD was associated with increased in-hospital mortality. There was a significant downtrend in the incidences of cardiac arrest, hemodialysis and length of stay in TMVR patients. Conclusion: Real world data showed a steady increase in the number of TMVR and SMVR procedures. Overall, TMVR was associated with low in-hospital mortality and complications rates. Despite older age and increased comorbidities, TMVR patients had lower in-hospital mortality and shorter length than their SMVR counterparts. © 2020
Authors & Co-Authors
Elbadawi, Ayman
United States, Galveston
The University of Texas Medical Branch at Galveston
Elgendy, Islam Y.
United States, Boston
Harvard Medical School
Mohamed, Ahmed H.
United States, Rochester
Rochester General Hospital
Almahmoud, Mohamed Faher
United States, Charleston
Medical University of South Carolina
Omer, Mohamed A.
United States, Minneapolis
Abbott Northwestern Hospital
Abuzaid, Ahmed Sami
United States, San Francisco
University of California, San Francisco
Mahmoud, Karim D.
United States, Houston
Houston Medical Center
Ogunbayo, Gbolahan O.
United States, Lexington
University of Kentucky
Denktaş, Ali Emin Emin
United States, Houston
Baylor School of Medicine
Paniagua, David
United States, Houston
Baylor School of Medicine
Banerjee, Subhash
United States, Dallas
Ut Southwestern Medical Center
Jneid, Hani M.
United States, Houston
Baylor School of Medicine
Statistics
Citations: 12
Authors: 12
Affiliations: 10
Identifiers
Doi:
10.1016/j.carrev.2020.05.021
ISSN:
15538389
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Randomised Control Trial
Cross Sectional Study
Participants Gender
Female