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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Observational study of the acceptability of Sayana® Press among intramuscular DMPA users in Uganda and Senegal
Contraception, Volume 89, No. 5, Year 2014
Notification
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Description
Background Sayana® Press (SP), a subcutaneous formulation of depot medroxyprogesterone acetate (DMPA) in Uniject™, has potential to be a valuable innovation in family planning (FP) because it may overcome logistic and safety challenges in delivering intramuscular DMPA (DMPA IM). However, SP's acceptability is unknown. We measured acceptability of SP among DMPA IM users. Study design This open-label observational study was conducted in clinics in three districts in Senegal and community-based distribution services in two districts in Uganda. Experienced DMPA IM users were offered SP by community health workers (CHWs) or clinic-based providers. SP decliners were asked to discuss their reasons. Those who received SP were interviewed pre- and postinjection and 3 months later, when they were asked if they would select SP over DMPA IM if it were available. Results One hundred twenty women in Uganda and 242 in Senegal received SP (117 and 240 were followed up, respectively). Nine Ugandan and seven Senegalese SP decliners were interviewed. Three months after receiving SP, 84% [95% confidence interval (CI)=75%-93%] of Ugandan participants and 80% (95% CI=74%-87%) of Senegalese participants said they would select SP over DMPA IM. Main reasons for selecting SP were fewer side effects, liking the method, fast administration, less pain and method effectiveness. Thirty-four adverse events were reported but were not serious. No pregnancies were reported. Conclusion Current DMPA IM users in Senegal and Uganda accepted SP, and most preferred SP over DMPA IM. SP can be safely introduced into FP programs and administered by trained CHWs, with expectation of client uptake. Implications We found SP acceptable and safe in diverse settings among current intramuscular DMPA users, including those who received SP from CHWs. This provides evidence that SP would be used and could therefore reduce unmet family planning needs if introduced into family planning programs. © 2014 Elsevier Inc.
Authors & Co-Authors
Burke, Holly Mc Clain
United States, Durham
Fhi 360
Mueller, Monique Peloquin
United States, Durham
Fhi 360
Perry, Brian
United States, Durham
Fhi 360
Packer, Catherine A.
United States, Durham
Fhi 360
Bufumbo, Leonard
United States, Durham
Fhi 360
Mbengue, Daouda
Senegal
Centre de Formation et de Recherche en Santé de la Reproduction (ceforep), Senegal Centre de Formation et de Recherche en Santé de la Reproduction (ceforep)
Mall, I.
Senegal
Centre de Formation et de Recherche en Santé de la Reproduction (ceforep), Senegal Centre de Formation et de Recherche en Santé de la Reproduction (ceforep)
Daff, Bocar Mamadou
Senegal, Action
Ministry of Health and Social
Mbonye, Anthony Kabanza
Uganda, Kampala
Uganda Ministry of Health
Statistics
Citations: 60
Authors: 9
Affiliations: 4
Identifiers
Doi:
10.1016/j.contraception.2014.01.022
ISSN:
00107824
e-ISSN:
18790518
Research Areas
Health System And Policy
Sexual And Reproductive Health
Study Locations
Senegal
Uganda
Participants Gender
Female