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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Aerosol and subcutaneous measles vaccine: Measles antibody responses 6 years after re-vaccination
Vaccine, Volume 25, No. 21, Year 2007
Notification
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Description
There are no large-scale data on the long-term persistence of measles antibody after vaccination by the aerosol route. We therefore followed-up South African schoolchildren 6 years after their re-vaccination with Edmonston-Zagreb (EZ) and Schwarz (SW) measles vaccine given by aerosol and subcutaneous routes. Measles antibody levels and the proportion of children who were seropositive at year 6 remained significantly higher in the Edmonston-Zagreb aerosol group compared to the groups that received Schwarz or Edmonston-Zagreb vaccine subcutaneously. Measles re-vaccination by aerosol evokes a stronger and much longer lasting antibody response than injected vaccine and should thus provide more durable protection against measles. © 2007 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Dilraj, Athmanundh
Unknown Affiliation
Sukhoo, Reshma
Unknown Affiliation
Cutts, Felicity T.
Unknown Affiliation
Bennett, John V.
Unknown Affiliation
Statistics
Citations: 64
Authors: 4
Affiliations: 4
Identifiers
Doi:
10.1016/j.vaccine.2007.03.003
ISSN:
0264410X
Research Areas
Infectious Diseases
Maternal And Child Health