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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Successful treatment of old world cutaneous leishmaniasis caused by Leishmania infantum with posaconazole
Antimicrobial Agents and Chemotherapy, Volume 55, No. 4, Year 2011
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Description
Old World cutaneous leishmaniasis is a widespread and potentially disfiguring protozoal infection that is endemic in the Mediterranean basin, Africa, and parts of Asia. Human infection is caused by several species of Leishmania parasites, such as Leishmania infantum. Available systemic and topical treatments vary in efficacy and are often unjustified due to their toxicity. We report on a case that was treated with posaconazole, a drug typically considered an antifungal agent but which also targets specific metabolic pathways of the parasite. Copyright © 2011, American Society for Microbiology. All Rights Reserved.
Authors & Co-Authors
Paniz Mondolfi, A. E.
United States, New York
Vagelos College of Physicians and Surgeons
Venezuela, Caracas
Universidad Central de Venezuela Instituto de Biomedicina
Stavropoulos, C.
United States, New York
Vagelos College of Physicians and Surgeons
Gelanew, Tesfaye
Germany, Berlin
Charité – Universitätsmedizin Berlin
Ethiopia, Addis Ababa
School of Medicine
Loucas, E.
United States, New York
Icahn School of Medicine at Mount Sinai
Perez Alvarez, A. M.
Venezuela, Caracas
Universidad Central de Venezuela Instituto de Biomedicina
Benaím, Gustavo
Venezuela, Caracas
Universidad Central de Venezuela, Facultad de Ciencias
Polsky, B.
United States, New York
Vagelos College of Physicians and Surgeons
Schoenian, G.
Germany, Berlin
Charité – Universitätsmedizin Berlin
Sordillo, E. M.
United States, New York
Vagelos College of Physicians and Surgeons
Statistics
Citations: 9
Authors: 9
Affiliations: 6
Identifiers
Doi:
10.1128/AAC.01498-10
ISSN:
00664804
e-ISSN:
10986596
Research Areas
Noncommunicable Diseases