Genotypic investigation of a rotavirus cluster at a quaternary-care pediatric hospital

Rotavirus (RV) was a common healthcare-associated infection prior to the introduction of the RV vaccine. Following widespread RV vaccination, healthcare-associated rotavirus cases are rare. We describe an investigation of a cluster of rotavirus infections in a pediatric hospital in which an uncommon genotype not typically circulating in the United States was detected. © The Author(s), 2023. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.