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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Value and utility of structured self-monitoring of blood glucose in real world clinical practice: Findings from a multinational observational study
Diabetes Technology and Therapeutics, Volume 14, No. 4, Year 2012
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Description
Background: The Structured Testing Program (STeP) study, a cluster-randomized, controlled trial, showed that a structured self-monitoring of blood glucose (SMBG)-based intervention improves clinical outcomes. It is important to determine whether this intervention can be adapted for use in general medical practice. This study examined the feasibility and effects of a modified version of the STeP intervention on clinical and attitudinal outcomes in real world clinical settings. Methods: In this 3-month, observational, multinational study, 375 type 1 and type 2 diabetes patients in 11 countries were asked to generate a blood glucose (bG) profile once per month for 3 consecutive months, using a paper-based bG analysis tool (Accu-Chek ® 360° View ® bG analysis system, Roche Diagnostics, Mannheim, Germany). Measurements were to be performed before and 2h after main meals and before bedtime on 3 consecutive days. End points included change from baseline in glycated hemoglobin (HbA1c) and other parameters of diabetes complications. Patient and physician attitudes toward use of the structured testing form were also assessed. Results: Reductions in mean (SD) HbA1c from baseline were significant, from 9.2% (1.6%) to 8.0% (1.4%) (Δ -1.2% [1.6%], P<0.001). Reductions in mean (SD) average bG from baseline were significant, from 189.5mg/dL (55.5mg/dL) to 153mg/dL (39.6mg/dL) (Δ-36.4mg/dL [52.5mg/dL], P<0.001). Significant (P<0.001) improvements in body mass index, lipids, and blood pressure were also observed. Patients and physicians were generally positive about the utility of the structured testing form. Conclusions: Use of the structured SMBG intervention is practical in real world clinical settings and is associated with improved diabetes management. © Copyright 2012, Mary Ann Liebert, Inc. 2012.
Authors & Co-Authors
Lalić, Nebojša Malić
Serbia, Belgrade
Clinic of Endocrinology
Tankova, Tsvetalina
Bulgaria, Sofia
University Hospital Alexandrovska
Nourredine, Mallem
Algeria, Batna
Clinic for Diabetology
Parkin, Christopher
United States, Boulder City
Cgparkin Communications, Inc
Schweppe, Ulrich
Germany, Penzberg
Roche Diagnostics Gmbh
Amann-Zalan, Ildiko
Germany, Penzberg
Roche Diagnostics Gmbh
Statistics
Citations: 25
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1089/dia.2011.0186
ISSN:
15209156
e-ISSN:
15578593
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Randomised Control Trial