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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
IMRT for breast. A planning study
Radiotherapy and Oncology, Volume 76, No. 3, Year 2005
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Description
Background and purpose: To evaluate the performance of ten different treatment-planning systems when intensity modulated (IMRT) plans are designed for breast treatments that include the irradiation of the internal mammary chain. Patients and methods: A dataset of five patients (CT images and volumes of interest) was distributed to design IMRT plans on the ten systems. To minimise biases, the same geometry and clinical planning aims were imposed on the individual plans. Results were analysed in terms of dose distributions and dose volume histograms. Results and conclusions: For target coverage, the volume receiving more than 95% of the prescribed dose ranged from 77% (OTP) to 91% (Eclipse and Pinnacle), the volume receiving more than 107% ranged from 3.3% (Hyperion) to 23.2% (OTP). The mean dose to ipsilateral lung ranged from 13 Gy (Eclipse) to 18 Gy (OTP). The volume of the contralateral breast receiving more than 10 Gy ranged from 3% (Pinnacle) to 26% (Precise). The volume of heart receiving more than 20 Gy ranged from 7% (Eclipse) to 47% (Precise), the maximum significant dose to heart ranged from ∼27 Gy (XiO) to ∼49 Gy (Precise). The maximum significant dose to healthy tissue ranged from ∼51 Gy (Eclipse) to ∼62 Gy (OTP). It was also possible to show that the treatment geometry proposed here enables to minimise contralateral breast irradiation while keeping minimal ipsilateral lung (or heart) involvement and satisfactory target coverage. © 2005 Elsevier Ireland Ltd. All rights reserved.
Authors & Co-Authors
Fogliata, Antonella
Switzerland, Bellinzona
Oncology Institute of Southern Switzerland
Nicolini, G.
Switzerland, Bellinzona
Oncology Institute of Southern Switzerland
Alber, Markus L.
Germany, Tubingen
Universitätsklinikum Und Medizinische Fakultät Tübingen
Asell, M.
Sweden, Stockholm
Elekta ab
Dobler, Barbara
Germany, Mannheim
Mannheim Gmbh
El-Haddad, M.
Germany, Mannheim
Mannheim Gmbh
Egypt, Cairo
Faculty of Medicine
Hårdemark, B.
Sweden, Stockholm
Raysearch Laboratories
Jelen, U.
Poland, Krakow
Agh University of Krakow
Kania, A.
United States
North American Scientifics Corporation
Larsson, M.
Sweden, Stockholm
Raysearch Laboratories
Lohr, Frank R.H.
Germany, Mannheim
Mannheim Gmbh
Munger, T.
Germany, Freiburg
Computerised Medical Systems Gmbh
Negri, E.
Italy, Novara
University Hospital of Novara
Rodrigues, C.
Netherlands, Eindhoven
Philips Healthcare Nederland
Cozzi, Luca
Switzerland, Bellinzona
Oncology Institute of Southern Switzerland
Statistics
Citations: 84
Authors: 15
Affiliations: 11
Identifiers
Doi:
10.1016/j.radonc.2005.08.004
Research Areas
Health System And Policy