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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Pregnancy outcome in HIV-positive women in Enugu, Nigeria
Journal of Obstetrics and Gynaecology, Volume 27, No. 3, Year 2007
Notification
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Description
This is a retrospective case-control study of 62 HIV-positive women and 100 HIV-negative controls who delivered in the University of Nigeria Teaching Hospital, Enugu, from 2 August, 2002 to 31 March, 2004. The HIV-positive women were relatively younger and of lower mean parity than the HIV-negative controls. They were also significantly more likely to have positive syphilis serology, higher mean duration of labour, perineal tear, puerperal sepsis and higher mean duration of hospital stay, higher prevalence of low birth weight, birth asphyxia and more admissions to the Newborn Special Care Unit than the controls (p < 0.05). However, there was no significant difference in the two groups in the prevalence of hepatitis B surface antigenaemia, recurrent vulvovaginitis, abortions, stillbirths, congenital anomalies, pre-term delivery, mean interval between rupture of membranes and delivery and mode of delivery (p > 0.05). All (100%) the HIV-negative and 96.8% of the seropositive women had voluntary counselling and testing (VCT). There was no maternal death in either group. Untreated maternal HIV infection is associated with adverse pregnancy outcomes in the form of increased maternal and fetal morbidities. Hence for optimal outcomes, prevention of mother-to-child transmission (PMTCT) programmes must incorporate combination drug treatment for the mother as early in pregnancy as possible. © 2007 Informa UK Ltd.
Authors & Co-Authors
Onah, Hyacinth Eze
Nigeria, Naukka
University of Nigeria
Nigeria, Enugu
General Post Office
Obi, Samuel Nnamdi
Nigeria, Naukka
University of Nigeria
Agbata, Tagbo Anthony
Nigeria, Naukka
University of Nigeria
Oguanuo, Theophilus Chimezie
Nigeria, Naukka
University of Nigeria
Statistics
Citations: 46
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1080/01443610701195108
ISSN:
01443615
e-ISSN:
13646893
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Case-Control Study
Study Locations
Nigeria
Participants Gender
Female