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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Parkinsonism in a population of northern Tanzania: A community-based door-to-door study in combination with a prospective hospital-based evaluation
Journal of Neurology, Volume 257, No. 5, Year 2010
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Description
The prevalence of Parkinson's disease (PD) in sub-Saharan Africa is still a matter of debate. The few studies that have been conducted have shown prevalences lower than those in the western world. Whether this represents a genuine finding is unclear to date. In northern Tanzania, we have conducted a hospital-based evaluation and a community-based door-to-door study to assess the prevalence of Parkinsonism, including that of PD. Over a period of 8 months, all patients admitted to a mid-size rural hospital were screened for PD. In parallel, 1,569 people aged ≥50 years were recruited from the communities and assessed for PD with standard questions. Sampling was performed according to the method of "multistage cluster sampling." The questions had previously been tested in a pilot study prior to the survey. People who screened positive were examined by a specialist neurologist. In the hospital, eight of 740 people with neurological diagnoses had Parkinsonism, of whom three patients had a diagnosis of PD. In the community-based study, 18 people answered positively to least one of the 12 screening questions. However, the diagnosis of PD could not be confirmed by further examination in any of them. The prevalence of PD in northern Tanzania was found to be very low. This result would need confirmation in studies with larger populations, ideally of different African ethnicities. © 2009 Springer-Verlag.
Authors & Co-Authors
Winkler, Andrea Sylvia
Germany, Munich
Ludwig-maximilians-universität München
Tanzania, Mbulu
Haydom Lutheran Hospital
Tütüncü, Esra
Germany, Ulm
Universität Ulm
Trendafilova, Anna
Germany, Ulm
Universität Ulm
Meindl, Michael
Austria, Innsbruck
Medizinische Universitat Innsbruck
Kaaya, John
Tanzania
District General Hospital
Schmutzhard, Erich
Austria, Innsbruck
Medizinische Universitat Innsbruck
Kassubek, Jan
Germany, Ulm
Universität Ulm
Statistics
Citations: 22
Authors: 7
Affiliations: 5
Identifiers
Doi:
10.1007/s00415-009-5420-z
ISSN:
03405354
e-ISSN:
14321459
Research Areas
Health System And Policy
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Tanzania