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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
arts and humanities
Calcium supplementation for the prevention of hypertensive disorders of pregnancy: current evidence and programmatic considerations
Annals of the New York Academy of Sciences, Volume 1510, No. 1, Year 2022
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Description
Most low- and middle-income countries present suboptimal intakes of calcium during pregnancy and high rates of mortality due to maternal hypertensive disorders. Calcium supplementation during pregnancy is known to reduce the risk of these disorders and associated complications, including preeclampsia, maternal morbidity, and preterm birth, and is, therefore, a recommended intervention for pregnant women in populations with low dietary calcium intake (e.g., where ≥25% of individuals in the population have intakes less than 800 mg calcium/day). However, this intervention is not widely implemented in part due to cost and logistical issues related to the large dose and burdensome dosing schedule (three to four 500-mg doses/day). WHO recommends 1.5–2 g/day but limited evidence suggests that less than 1 g/day may be sufficient and ongoing trials with low-dose calcium supplementation (500 mg/day) may point a path toward simplifying supplementation regimens. Calcium carbonate is likely to be the most cost-effective choice, and it is not necessary to counsel women to take calcium supplements separately from iron-containing supplements. In populations at highest risk for preeclampsia, a combination of calcium supplementation and food-based approaches, such as food fortification with calcium, may be required to improve calcium intakes before pregnancy and in early gestation. © 2022 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of New York Academy of Sciences.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC9306576/bin/NYAS-1510-52-s001.docx
Authors & Co-Authors
Ashorn, Per A.
Finland, Tampere
Tampere University
Askari, Sufia
United Kingdom, London
Children's Investment Fund Foundation
Belizán, J.
Argentina, Buenos Aires
Consejo Nacional de Investigaciones Científicas y Técnicas
Boy, Erick
United States, Washington, D.c.
International Food Policy Research Institute
Cormick, Gabriela
Argentina, Buenos Aires
Consejo Nacional de Investigaciones Científicas y Técnicas
Dickin, Katherine L.
United States, Ithaca
Cornell University
Fawzi, Wafaie W.
United States, Boston
Harvard T.h. Chan School of Public Health
Hofmeyr, George Justus
Botswana, Gaborone
University of Botswana
South Africa
Walter Sisulu University
Humphrey, Jean H.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Khadilkar, Anuradha Vaman
India, Pune
Jehangir Hospital, Pune
Neufeld, Lynnette Marie
Switzerland, Geneva
Global Alliance for Improved Nutrition
Palacios, Cristina
United States, Miami
Florida International University
Roth, Daniel E.
Canada, Toronto
University of Toronto
Sudfeld, Christopher Robert
United States, Boston
Harvard T.h. Chan School of Public Health
Statistics
Citations: 9
Authors: 14
Affiliations: 17
Identifiers
Doi:
10.1111/nyas.14733
ISSN:
00778923
Research Areas
Food Security
Maternal And Child Health
Noncommunicable Diseases
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cross Sectional Study
Participants Gender
Female