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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Marjolin's ulcer: The importance of surgical management of chronic cutaneous ulcers
International Journal of Dermatology, Volume 46, No. SUPPL. 2, Year 2007
Notification
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Description
Chronic cutaneous ulcers are commonplace in the developing world, especially in rural areas with poor living conditions and often result from the trauma of road-traffic injuries. Chronic cutaneous ulcers may also be due to vascular insufficiency, neuropathy, nodular leprosy, pressure, diabetes, or hemoglobinopathies, or they may be tropical ulcers. If poorly managed, these lesions may undergo malignant transformation. We evaluated the clinical histories and treatment outcomes of patients seen at the University of Calabar Teaching Hospital, between January 2000 and December 2004, who had histologic diagnosis of Marjolin's ulcer, in an attempt to identify risk factors for this problem. The six patients were men, age 30-70 years (mean, 42 years). Trauma was the leading cause of injury leading to ulceration: road-traffic accidents (four patients, 66.7%), fall (one patient, 16.7%), and flame burn (one patient, 16.7%). Most injuries involved the limbs: lower (four patients, 66.7%) and upper (one patient, 16.7%). The histologic diagnosis in all the cases were squamous cell carcinoma and mean latency period from injury to diagnosis of malignancy was 18.5 years. All the patients had been admitted because of poor results from topical treatment. Three patients (50%) were managed with wide excision and skin grafting with the lesions healed. Ignorance as well as economic and sociocultural factors were the underlying issues. Education concerning the risks associated with chronic wounds and the need for prompt and proper surgical management are recommended. © 2007 The Authors Journal compilation © 2007 The International Society of Dermatology.
Authors & Co-Authors
Asuquo, M. E.
Nigeria, Calabar
University of Calabar
Ugare, Gabriel
Nigeria, Calabar
University of Calabar
Ebughe, Godwin
Nigeria, Calabar
University of Calabar
Jibril, Paul
Nigeria, Calabar
University of Calabar
Statistics
Citations: 59
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1111/j.1365-4632.2007.03382.x
ISSN:
00119059
e-ISSN:
13654632
Research Areas
Cancer
Health System And Policy
Noncommunicable Diseases
Violence And Injury
Participants Gender
Male