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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Serum ferritin and vitamin D in female hair loss: Do they play a role?
Skin Pharmacology and Physiology, Volume 26, No. 2, Year 2013
Notification
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Description
Aim: Evaluation of serum ferritin and vitamin D levels in females with chronic telogen effluvium (TE) or female pattern hair loss (FPHL), in order to validate their role in these common hair loss diseases. Methods: Eighty females (18 to 45 years old) with hair loss, in the form of TE or FPHL, and 40 age-matched females with no hair loss were included in the study. Diagnosis was based upon clinical examination as well as trichogram and dermoscopy. Serum ferritin and vitamin D2 levels were determined for each participant. Results: Serum ferritin levels in the TE (14.7 ± 22.1 μg/l) and FPHL (23.9 ± 38.5 μg/l) candidates were significantly lower than in controls (43.5 ± 20.4 μg/l). Serum vitamin D2 levels in females with TE (28.8 ± 10.5 nmol/l) and FPHL (29.1 ± 8.5 nmol/l) were significantly lower than in controls (118.2 ± 68.1 nmol/l; p < 0.001). These levels decreased with increased disease severity. Serum ferritin cut-off values for TE and FPHL were 27.5 and 29.4 μg/l, respectively, and those for vitamin D were 40.9 and 67.9 nmol/l. Conclusion: Low serum ferritin and vitamin D2 are associated with hair loss in females with TE and FPHL. Screening to establish these levels in cases of hair loss and supplementing with them when they are deficient may be beneficial in the treatment of disease. © 2013 S. Karger AG, Basel.
Authors & Co-Authors
Rasheed, Hoda M.
Egypt, Cairo
Departments of Dermatology
Mahgoub, Doaa
Egypt, Cairo
Departments of Dermatology
Hegazy, Rehab Aly
Egypt, Cairo
Departments of Dermatology
El-Komy, Mohamed Hussein Medhat
Egypt, Cairo
Departments of Dermatology
Abdel Hay, Rania Mounir A.
Egypt, Cairo
Departments of Dermatology
Hamid, M. A.
Egypt, Cairo
Departments of Dermatology
Hamdy, Enas S.
Egypt, Cairo
Faculty of Medicine
Statistics
Citations: 108
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.1159/000346698
ISSN:
16605527
e-ISSN:
16605535
Participants Gender
Female