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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Validity of the depressive dimension extracted from principal component analysis of the PANSS in drug-free patients with schizophrenia
Schizophrenia Research, Volume 56, No. 1-2, Year 2002
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Description
Depressive symptoms frequently occur during the course of schizophrenia. This study explored the relationships between the schizophrenia symptomatology and three measures of depression. Eighty-one drug-free inpatients with acute schizophrenia were assessed with the positive and negative syndrome scale (PANSS), the Calgary depression scale for schizophrenia (CDSS), and the Hamilton rating scale for depression (HAM-D). The depressive subscale of PANSS (PANSS-D) was also considered as a third scale for measuring depression. A principal component analysis (PCA) of PANSS items identified five clinical dimensions of schizophrenia called 'negative', 'positive', 'anxio-depressive', 'excitement', and 'disorganisation and others'. Our anxio-depressive dimension (PANSS-ad) was strictly identical with the PANSS-D. Scores on CDSS and HAM-D were highly inter-correlated and highly correlated with the PANSS-ad. Furthermore, while scores on CDSS were correlated only with this dimension, scores at HAM-D were also positively correlated with the negative dimension and negatively correlated with the excitement dimension. In conclusion, our results suggest that PANSS evaluation itself may be sufficient to give a correct approximation of the depression in patients with schizophrenia. However, depression scales are of course needed to assess specifically depressive symptoms in patients with schizophrenia; hence, the CDSS could be a more specific instrument than HAM-D. © 2002 Elsevier Science B.V. All rights reserved.
Authors & Co-Authors
El Yazaji, Meriem
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Battas, Omar
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Agoub, Mohamed
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Moussaoui, Driss
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Gutknecht, Christel
France, Villeurbanne
Université Claude Bernard Lyon 1
Daléry, Jean
France, Villeurbanne
Université Claude Bernard Lyon 1
D’lAmato, Thierry
France, Villeurbanne
Université Claude Bernard Lyon 1
Saoud, Mohamed
France, Villeurbanne
Université Claude Bernard Lyon 1
France, Paris
Inserm
Statistics
Citations: 75
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1016/S0920-9964(01)00247-X
ISSN:
09209964
Research Areas
Mental Health