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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
pharmacology, toxicology and pharmaceutics
Bioassay-guided isolation and identification of antifungal compounds from ginger
Phytotherapy Research, Volume 17, No. 8, Year 2003
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Description
A bioassay-guided isolation of antifungal compounds from an African land race of ginger, Zingiber officinale Roscoe, led to the identification of [6], [8] and [10]-gingerols and [6]-gingerdiol as the main antifungal principles. The compounds were active against 13 human pathogens at concentrations of <1 mg/mL. The gingerol content of the African land race was at least 3 × higher than that of typical commercial cultivars of ginger. Therefore, ginger extracts standardized on the basis of the identified compounds, could be considered as antifungal agents for practical therapy. Copyright © 2003 John Wiley & Sons, Ltd.
Authors & Co-Authors
Ficker, Christine E.
Unknown Affiliation
Smith, Myron L.
Unknown Affiliation
Akpagana, Koffi
Unknown Affiliation
Gbéassor, Menssanvi F.
Unknown Affiliation
Durst, Tony
Unknown Affiliation
Arnason, John Thor A.
Canada, Ottawa
University of Ottawa
Statistics
Citations: 80
Authors: 6
Affiliations: 1
Identifiers
Doi:
10.1002/ptr.1335
ISSN:
0951418X