Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Oral candidiasis and hairy leukoplakia correlate with HIV infection in Tanzania
Oral Surgery Oral Medicine and Oral Pathology, Volume 69, No. 5, Year 1990
Notification
URL copied to clipboard!
Description
We report a detailed study on oral lesions and their association with the WHO revised provisional case definition of AIDS as well as serologic signs of HIV infection among 186 patients in Dar Es Salaam, Tanzania. The patient material consisted of 39 hospitalized suspected AIDS patients, 44 medical nonsuspected patients, 53 dental outpatients, and 50 patients with sexually transmitted diseases. The male:female ratio was 2.1:1 on average. Oral examination was done without knowledge of the HIV status of the patients. Among 39 suspected AIDS patients 97% had WHO AIDS criteria and 90% were seropositive for HIV. Among the 147 patients not suspected of having AIDS 18 (12%) had AIDS criteria and 15% had serologic evidence of HIV infection. The presence of WHO AIDS criteria correlated significantly with the presence of HIV antibodies, but not with HIV antigen. Oral lesions were found in 54% of those with AIDS criteria and 52% of HIV-infected patients, as compared to 3% and 6% of the patients without AIDS criteria and HIV infection, respectively (p < 0.01). Among patients with AIDS atrophic candidiasis occurred in 21%, pseudomembranous candidiasis in 23%, hairy leukoplakia in 36%, herpetic stomatitis in 2%, Kaposi's sarcoma in 4%, and nonspecific ulcer in 4%. The presence of oral lesions had a high predictive value for presence of AIDS criteria as well as for presence of HIV infection in this hospital setting. All patients should have a thorough oral examination and the presence of the aforementioned oral lesions should lead to testing for HIV infection. © 1990.
Authors & Co-Authors
Schiödt, Morten
Denmark, Copenhagen
Copenhagen University Hospital
Denmark, Copenhagen
Tandlægeskolen
United States, San Francisco
University of California, San Francisco
Bakilana, Poul B.
Tanzania, Dar es Salaam
Muhimbili Medical Center (mmc)
Hiza, John F.R.
Tanzania, Dar es Salaam
Muhimbili Medical Center (mmc)
Shao, John F.
Tanzania, Dar es Salaam
Mmc
Bygbjerg, Ib Christian
Denmark, Copenhagen
Copenhagen University Hospital
Mbaga, Idi M.
Tanzania, Dar es Salaam
Mmc
Vestergaard, Bent Faber
Denmark, Copenhagen
Statens Serum Institut
Nielsen, Carsten Möller
Denmark, Copenhagen
Statens Serum Institut
Lauritzen, Edgar
Denmark, Copenhagen
Ssi
Lerche, Brian
Denmark, Copenhagen
Copenhagen University Hospital
Kuijlen, Kirsten
Tanzania, Dar es Salaam
Nordic Clinic
Statistics
Citations: 73
Authors: 11
Affiliations: 8
Identifiers
Doi:
10.1016/0030-4220(90)90242-k
Research Areas
Cancer
Health System And Policy
Infectious Diseases
Study Locations
Tanzania
Participants Gender
Male
Female