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AFRICAN RESEARCH NEXUS

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immunology and microbiology

The complete genome sequence of the lumpy skin disease virus vaccine Herbivac LS reveals a mutation in the superoxide dismutase gene homolog

Archives of Virology, Volume 164, No. 12, Year 2019

The lumpy skin disease virus (LSDV) vaccine, Herbivac LS, batch 008, was sequenced and found to differ from the Neethling vaccine strain in the locus encoding a superoxide dismutase (SOD) homolog. The presence of a SOD homolog, be it full-length (as in Herbivac LS) or truncated (as in Neethling) may affect vaccine immunogenicity.

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Citations: 14
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Research Areas
Cancer
Genetics And Genomics