Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Effect of non-pharmacologic vitamin D status correction on circulating bone markers in healthy overweight and obese saudis
Molecules, Volume 18, No. 9, Year 2013
Notification
URL copied to clipboard!
Description
While moderate to severe vitamin D deficiency is prevalent in Saudi Arabia, skeletal effects associated with this deficiency are not common in this population. In this interventional study we measured the effects of improving vitamin D status on bone biochemical markers in overweight and obese adult Saudis. A total of 47 volunteers (21 males, 26 females) out of the initial 95 subjects were given verbal advice to expose themselves to sunlight for 5-30 min twice weekly and were encouraged to increase their intake of vitamin D-rich foods. Serum 25(OH)D, osteocalcin, and type 1 collagen cross-linked C-telopeptide (CTx), were measured at baseline and after one year. A significant decrease in the prevalence of vitamin D deficiency was observed (44% to 27%) after one year follow-up (p = 0.025). Also, a parallel significant increase in osteocalcin and a decrease in CTX and osteoprotegerin were observed. The results suggest that a modest increase in vitamin D levels among overweight and obese subjects through the promotion of lifestyle changes for one year have marginal effects in bone turnover markers as well as obesity itself. © 2013 by the authors.
Authors & Co-Authors
Al-Daghri, N. Mohammad
Saudi Arabia, Riyadh
College of Sciences
Saudi Arabia, Riyadh
King Saud University
Alkharfy, Khalid Mohammad
Saudi Arabia, Riyadh
College of Sciences
Saudi Arabia, Riyadh
King Saud University
Saudi Arabia, Riyadh
College of Pharmacy
Al-Othman, Abdulaziz M.
Saudi Arabia, Riyadh
King Saud University
Saudi Arabia, Riyadh
College of Applied Medical Sciences
Yakout, Sobhy M.
Saudi Arabia, Riyadh
King Saud University
al-Saleh, Yousef M.
Saudi Arabia, Riyadh
King Saud University
Fouda, Mona A.
Saudi Arabia, Riyadh
King Khalid University Hospital
Sabico, Shaun
Saudi Arabia, Riyadh
College of Sciences
Statistics
Citations: 11
Authors: 7
Affiliations: 5
Identifiers
Doi:
10.3390/molecules180910671
e-ISSN:
14203049
Research Areas
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Female