Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Physiologic predictors for the need for patch closure in neonatal congenital diaphragmatic hernia
Pediatric Surgery International, Volume 24, No. 6, Year 2008
Notification
URL copied to clipboard!
Description
Technically expedient repair of CDH defects is desirable. With increasing trend toward thoracoscopic repair, herein we examine physiologic predictors for the need for patch closure (PC) versus primary closure. All neonates who underwent surgical repair of CDH defects in a geographically defined region between 1992 and 2002 were included (n = 210). Two groups of patients were compared, primary repair (PR) versus PC. The 25th quartile was used as a cut off point for continuous variables. Univariate and multivariate logistic regression were performed. One hundred and fifty neonates underwent open PR (71.43%) versus 28.57% had PC. On univariate analyses the following variables were significantly associated with the need for PC: prenatal diagnosis, birth weight <2.7 kg, gestational age <37 weeks, APGAR at 5 min <6, immediate postnatal PCO2 >34, Immediate oxygen saturation <93%, use of Nitric oxide and the need for high frequency oscillation (HFO). On multivariate analyses, only a PCO2 >34 and the need for HFO were significantly associated with PC. Neonates with an initial PCO2 >34 or need HFO pre-operatively should be excluded from attempts to repair the CDH thoracoscopically based on their higher potential need for PC with its entailed technical difficulty and increased operative time. © 2008 Springer-Verlag.
Authors & Co-Authors
Zamakhshary, Mohammed Fouad
Canada, Toronto
Hospital for Sick Children University of Toronto
Saudi Arabia, Riyadh
King Abdulaziz Medical City - Riyadh
Mah, V. Kandice
Canada, Toronto
Hospital for Sick Children University of Toronto
Mah, Doug Y.
Canada, Toronto
Hospital for Sick Children University of Toronto
Cameron, Brian H.
Canada, Hamilton
Mcmaster University
Bohn, D.
Canada, Toronto
Hospital for Sick Children University of Toronto
Bass, Juan
Canada, Ottawa
Children's Hospital of Eastern Ontario, Ottawa
Scott, Leslie
Canada, London
Children's Hospital of Western Ontario
Kim, Peter C.W.
Canada, Toronto
Hospital for Sick Children University of Toronto
Statistics
Citations: 10
Authors: 8
Affiliations: 5
Identifiers
Doi:
10.1007/s00383-008-2152-6
ISSN:
01790358
Research Areas
Health System And Policy
Maternal And Child Health
Study Approach
Qualitative