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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of serological markers against measles, rubella, varicella, hepatitis B, hepatitis C, and human immunodeficiency virus among medical residents in mexico
Preventive Medicine, Volume 32, No. 5, Year 2001
Notification
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Description
Background. Vaccination programs among health care workers are based on seroprevalence studies, which seldom include medical residents or students. The objective of this study was to determine the sero-prevalence of antibodies against measles, rubella, varicella, hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) among medical residents. Methods. This study was designed as a prospective survey. A self-reported questionnaire was used to obtain the information. Serum samples were tested for antibodies by commercial immunoenzymatic assays. Statistical analysis was descriptive; history of exposure was evaluated as a diagnostic test and sensitivity, specificity, and predictive values were calculated according to Bayes theorem. Results. Eighty-nine residents were included, the median age was 27 years, and 58 (65.2%) were female. Seventy-two (79.7%) had been vaccinated against HBV, but vaccination was complete in only 30/72 (41.6%). All were positive for measles and varicella, with the exception of one case for each. The serology for rubella was negative in 12 residents (10 women). Three residents had anti-core against HBV, with negative surface antigen. One positive case for HCV was confirmed by Western blot. All were negative for HIV. A history of prior varicella had a 100% positive predictive value; in contrast, the negative predictive value was quite low (7%). Conclusions. Negative serology for rubella among women and incomplete vaccination against HBV support the implementation of vaccination programs in medical schools in Mexico. © 2001 American Health Foundation and Academic Press.
Authors & Co-Authors
Villasís-Keever, Miguel Angel
South Africa, Johannesburg
Epidemiology Research Unit
Peña, Luis Alberto
Unknown Affiliation
Miranda-Novales, Guadalupe
Mexico
Hospital Epidemiology Research Unit
Alvarez y Muñoz, Teresa
Unknown
Infectious and Parasitic Diseases Research Unit
Damasio-Santana, Leticia
Unknown
Infectious and Parasitic Diseases Research Unit
López-Fuentes, Georgina
Mexico, Mexico
Umae Hospital de Pediatría Centro Medico Nacional Siglo Xxi
Girón-Carrillo, Jorge Luis
Unknown Affiliation
Statistics
Citations: 34
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1006/pmed.2001.0825
ISSN:
00917435
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Participants Gender
Female