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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acceptability and adherence of a candidate microbicide gel among high-risk women in Africa and India
Culture, Health and Sexuality, Volume 12, No. 7, Year 2010
Notification
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Description
Vaginal microbicides currently under development are substances that may prevent the transmission of HIV. Qualitative, in-depth post-trial interview data from a Phase III clinical trial of 6% Cellulose Sulfate microbicide gel in two sites in Africa (Uganda and Benin) and two in India (Chennai and Bagalkot) were examined in order to better understand factors that influence microbicide acceptability and adherence in a clinical trial setting. Women found the gel relatively easy to use with partners with whom there were no expectations of fidelity, in situations where they had access to private space and at times when they were expecting to engage in sexual intercourse. Adherence to gel seemed significantly more difficult with primary partners due to decreased perceptions of risk, inconvenience or fear of partner disapproval. Findings suggest that women in a variety of settings may find a microbicide gel to be highly acceptable for its lubricant qualities and protective benefits but that adherence and consistent use may depend greatly on contextual and partner-related factors. These findings have important implications for future trial designs, predicting determinants of microbicide use and acceptability and marketing and educational efforts should a safe and efficacious microbicide be found. © 2010 Taylor & Francis.
Authors & Co-Authors
Greene, Elizabeth
United States, Durham
Fhi 360
Batona, Georges
Canada, Quebec
Université Laval
Hallad, Jyoti S.
India, Dharwad
Jss Institute of Economic Research
Johnson, Sethulakshmi C.
India, Chennai
Yr Gaitonde Centre for Aids Research and Education
Neema, Stella
Uganda, Kampala
Makerere University
Tolley, Elizabeth Ellen
United States, Durham
Fhi 360
Statistics
Citations: 69
Authors: 6
Affiliations: 5
Identifiers
Doi:
10.1080/13691051003728599
ISSN:
13691058
e-ISSN:
14645351
Research Areas
Health System And Policy
Infectious Diseases
Sexual And Reproductive Health
Study Approach
Qualitative
Study Locations
Benin
Uganda
Participants Gender
Female