Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
International guidelines for the in vivo assessment of skin properties in non-clinical settings: Part 1. pH
Skin Research and Technology, Volume 19, No. 2, Year 2013
Notification
URL copied to clipboard!
Description
Background: Skin surface pH is known to influence the dissolution and partitioning of chemicals and may influence exposures that lead to skin diseases. Non-clinical environments (e.g. workplaces) are highly variable, thereby presenting unique measurement challenges that are not typically encountered in clinical settings. Hence, guidelines are needed for consistent measurement of skin surface pH in environments that are difficult to control. Methods: An expert workshop was convened at the 5th International Conference on Occupational and Environmental Exposure of Skin to Chemicals to review available data on factors that could influence the determination of skin surface pH in non-clinical settings with emphasis on the workplace as a worst case scenario. Results: The key elements of the guidelines are: (i) minimize, to the extent feasible, the influences of relevant endogenous (anatomical position, skin health, time of day), exogenous (hand washing, barrier creams, soaps and detergents, occlusion), environmental (seasonality), and measurement (atmospheric conditions) factors; (ii) report pH measurements results as a difference or percent change (not absolute values) using a measure of central tendency and variability; and (iii) report notable deviations from these guidelines and other relevant factors that may influence measurements. Conclusion: Guidelines on the measurement and reporting of skin surface pH in non-clinical settings should promote consistency in data reporting, facilitate inter-comparison of study results, and aid in understanding and preventing occupational skin diseases. © 2012 John Wiley & Sons A/S.
Authors & Co-Authors
Stefaniak, Aleksandr Byron
United States, Washington, D.c.
National Institute for Occupational Safety and Health
Du Plessis, Johan Lodewykus
South Africa, Potchefstroom
North-west University
John, Swen
Germany, Osnabruck
Osnabrück University
Eloff, Fritz
South Africa, Potchefstroom
North-west University
Agner, Tove
Denmark, Copenhagen
Københavns Universitet
Chou, Tzu Chieh
Taiwan, Taichung
China Medical University
Nixon, Rosemary
Australia, Melbourne
Victoria's Skin and Cancer Foundation
Steiner, Markus F.C.
United Kingdom, Aberdeen
University of Aberdeen
Kudla, Irena
Canada, Toronto
Saint Michael's Hospital University of Toronto
Holness, Linn
Canada, Toronto
Saint Michael's Hospital University of Toronto
Statistics
Citations: 10
Authors: 10
Affiliations: 8
Identifiers
Doi:
10.1111/srt.12016
ISSN:
0909752X
e-ISSN:
16000846