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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Prevalence of BPH and lower urinary tract symptoms in West Africans
Prostate Cancer and Prostatic Diseases, Volume 15, No. 2, Year 2012
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Description
BACKGROUND: BPH and lower urinary tract symptoms (LUTS) are very common among older men in Western countries. However, the prevalence of these two conditions in the developing countries is less clear. METHODS: We assessed the age-standardized prevalence of BPH and/or LUTS among West Africans in a probability sample of 950 men aged 50-74 in Accra, Ghana, with no evidence of biopsy-confirmed prostate cancer after screening with PSA and digital rectal examination (DRE). Information on LUTS was based on self-reports of the International Prostate Symptom Score (IPSS). BPH was estimated using DRE, PSA levels and imputed prostate volume. RESULTS: The prevalence of DRE-detected enlarged prostate was 62.3%, while that of PSA≥1.5 ng ml -1 (an estimate of prostate volume ≥ 30 cm 3) was 35.3%. The prevalence of moderate-to-severe LUTS (IPSS≥8) was 19.9%. The prevalence of IPSS≥8 and an enlarged prostate on DRE was 13.3%. Although there is no universally agreed-upon definition of BPH/LUTS, making comparisons across populations difficult, BPH and/or LUTS appear to be quite common among older Ghanaian men. CONCLUSIONS: We found that after age standardization, the prevalence of DRE-detected enlarged prostate in Ghanaian men is higher than previously reported for American men, but the prevalence of LUTS was lower than previously reported for African Americans. Further studies are needed to confirm these findings and identify the risk factors for BPH in both Africans and African Americans. © 2012 Macmillan Publishers Limited All rights reserved.
Authors & Co-Authors
Chokkalingam, Anand P.
United States, Berkeley
University of California, Berkeley
Yeboah, Edward D.
Ghana, Accra
University of Ghana
DeMarzo, A.
United States, Baltimore
Johns Hopkins Medicine
Netto, G.
United States, Baltimore
Johns Hopkins Medicine
Yu, Kai
United States, Rockville
National Cancer Institute Nci
Biritwum, Richard Berko
Ghana, Accra
University of Ghana
Tettey, Yao
Ghana, Accra
University of Ghana
Adjei, Andrew Anthony
Ghana, Accra
University of Ghana
Jadallah, S.
United States, Baltimore
Johns Hopkins Medicine
Li, Yan
United States, Rockville
National Cancer Institute Nci
Chu, Lisa W.
United States, Rockville
National Cancer Institute Nci
Chia, D.
United States, Los Angeles
University of California, Los Angeles
Niwa, Shelley
United States, Rockville
Westat, Inc.
Partin, Alan Wayne
United States, Baltimore
Johns Hopkins Medicine
Thompson, Ian Murchie
United States, San Antonio
University of Texas Health Science Center at San Antonio
Roehrborn, C.
United States, Dallas
Ut Southwestern Medical Center
Hoover, Robert N.
United States, Rockville
National Cancer Institute Nci
Hsing, Ann Wu
United States, Rockville
National Cancer Institute Nci
Statistics
Citations: 54
Authors: 18
Affiliations: 8
Identifiers
Doi:
10.1038/pcan.2011.43
ISSN:
13657852
e-ISSN:
14765608
Research Areas
Cancer
Study Design
Cross Sectional Study
Study Locations
Ghana
Participants Gender
Male