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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Ethical issues posed by cluster randomized trials in health research
Trials, Volume 12, Article 100, Year 2011
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Description
The cluster randomized trial (CRT) is used increasingly in knowledge translation research, quality improvement research, community based intervention studies, public health research, and research in developing countries. However, cluster trials raise difficult ethical issues that challenge researchers, research ethics committees, regulators, and sponsors as they seek to fulfill responsibly their respective roles. Our project will provide a systematic analysis of the ethics of cluster trials. Here we have outlined a series of six areas of inquiry that must be addressed if the cluster trial is to be set on a firm ethical foundation© 2011 Weijer et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Weijer, Charles
Canada, London
Western University
Grimshaw, Jeremy M.
Canada, Ottawa
Ottawa Hospital Research Institute
Canada, Ottawa
University of Ottawa
Taljaard, Monica K.
Canada, Ottawa
Ottawa Hospital Research Institute
Canada, Ottawa
University of Ottawa
Donner, Allan P.
Canada, London
Western University
Canada, London
Robarts Research Institute
Eccles, Martin Paul
United Kingdom, Newcastle
Newcastle University
Zwarenstein, Merrick F.
Canada, Toronto
Sunnybrook Health Sciences Centre
Statistics
Citations: 122
Authors: 6
Affiliations: 8
Identifiers
Doi:
10.1186/1745-6215-12-100
ISSN:
17456215
Study Design
Randomised Control Trial
Study Approach
Systematic review