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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Considerations for introduction of a Rotavirus vaccine in Oman: Rotavirus disease and economic burden
Journal of Infectious Diseases, Volume 200, No. SUPPL. 1, Year 2009
Notification
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Description
Rotavirus is the most common cause of fatal childhood diarrhea worldwide. We provide the first estimates of the health care and economic burden of severe rotavirus disease in Oman. We conducted active, hospitalbased surveillance of rotavirus disease at 11 regional public hospitals in Oman, using the guidelines suggested by the generic World Health Organization protocol. From July 2006 through June 2008, all children aged <5 years who were hospitalized for acute gastroenteritis were enrolled in the surveillance program, and their stool samples were tested for rotavirus using a commercially available enzyme immunoassay (ID EIA Rotavirus Test; Dako Diagnostics). Rotavirus was detected in samples from 1712 (49%) of 3470 children. These children were hospitalized for a median of 3 days for severe diarrhea. A marked seasonal peak was evident with a majority of the cases occurring from December through May. Of the rotavirus cases, 69% occurred in children aged 6-17 months. We identified a diverse strain pattern in Oman, with G2 (37%), G1 (38%), and G9 (11%) accounting for most of typeable strains. By our burden estimates, the Omani government spends an estimated US$791,817 and US$1.8 million annually to treat rotavirus-associated diarrhea in the outpatient and hospital settings, respectively. A rotavirus vaccination program might substantially reduce the burden of severe diarrhea among children in Oman. © 2009 by the Infectious Diseases Society of America. All rights reserved.
Authors & Co-Authors
Al-Awaidy, Salah Thabit
Unknown Affiliation
Bawikar, Shyam Pandurang
Unknown Affiliation
Al-Busaidy, S. M.
Unknown Affiliation
Baqiani, S.
Unknown Affiliation
Al Abedani, I.
Unknown Affiliation
Varghese, R.
Unknown Affiliation
Abdoan, H. S.
Unknown Affiliation
Al Abdoon, H.
Unknown Affiliation
Bhatnagar, Sonika
Unknown Affiliation
Al Hasini, K. S.
Unknown Affiliation
Mohan, P.
Unknown Affiliation
Shah, Syed
Unknown Affiliation
Elamir, E.
Unknown Affiliation
Klena, John David
Unknown Affiliation
Ahmed, Salwa Fouad
Unknown Affiliation
Teleb, Nadia A.
Unknown Affiliation
Parashar, Umesh D.
Unknown Affiliation
Patel, Manish M.
Unknown Affiliation
Statistics
Citations: 36
Authors: 18
Affiliations: 8
Identifiers
Doi:
10.1086/605339
ISSN:
00221899
Research Areas
Health System And Policy
Maternal And Child Health