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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
The threat of peste des petits ruminants: progress in vaccine development for disease control
Vaccine, Volume 25, No. 30 SPEC. ISS., Year 2007
Notification
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Description
Peste des petits ruminants (PPR) is a highly contagious animal disease caused by a virus in the genus Morbillivirus, family Paramyxoviridae. This infection is responsible for high morbidity and mortality in sheep and goats and in some small wild ruminant species. The huge number of small ruminants, which are reared in the endemic areas makes PPR a serious disease threatening the livelihood of poor farmers. Taking advantage of the closely relationship between rinderpest and PPR viruses, the attenuated rinderpest vaccine was used in the control of PPR. It is now replaced by the homologous attenuated PPR vaccine. Unfortunately, animals that have received this vaccine cannot be distinguished serologically from infected animals. With the advent of DNA recombinant technology, efforts are being made to develop effective PPR marker vaccines to enable such differentiation and which would allow countries to implement both vaccination and disease surveillance programmes at the same time. © 2007 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Diallo, Adama
Austria, Vienna
International Atomic Energy Agency, Vienna
Minet, Cécile
France, Montferrier-sur-lez
Animal, Santé, Territoires, Risques et Ecosystèmes Astre
Le Goff, Christian
France, Montferrier-sur-lez
Animal, Santé, Territoires, Risques et Ecosystèmes Astre
Berhe, G.
Ethiopia
Nvi
Albina, Emmanuel
France, Montferrier-sur-lez
Animal, Santé, Territoires, Risques et Ecosystèmes Astre
Libeau, Geneviève
France, Montferrier-sur-lez
Animal, Santé, Territoires, Risques et Ecosystèmes Astre
Barrett, Thomas
United Kingdom, Surrey
The Pirbright Institute
Statistics
Citations: 210
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1016/j.vaccine.2007.02.013
ISSN:
0264410X
Research Areas
Genetics And Genomics