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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Percutaneous mitral valvotomy versus closed surgical commissurotomy. Up to 15 years of follow-up of a prospective randomized study
Journal of Cardiology, Volume 53, No. 1, Year 2009
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Description
Background: Immediate and intermediate term results of percutaneous mitral valvotomy (PMV) are comparable to closed surgical commissurotomy (CSC). We aimed at exploring this relation in the long term. Methods: Previously, we randomized 40 consecutive patients with moderate to severe mitral stenosis [defined as mitral valve area (MVA) less than 1.5 cm2] to undergo either PMV (PMV group = 20 patients) or CSC (CSC group = 20 patients). For all patients, full echocardiographic assessment was performed before the procedure/operation. Patients assigned to PMV underwent the double balloon technique. Echocardiographic assessment was done following both procedures before discharge and repeated 1 and 6 months later. Echocardiographic follow-up was performed, thereafter, on a yearly basis for up to 15 years, with a mean follow-up period of 99 ± 12 months. Results: Immediate echocardiographic results showed no statistically significant difference between the 2 groups regarding the final MVA or mean diastolic gradient across the mitral valve. Two patients dropped out from the CSC group and one from the PMV group. MVA was 1.8 ± 0.3 cm2 versus 1.8 ± 0.4 cm2 (p > 0.05) and mean diastolic pressure gradient across the mitral valve was 7 ± 4 mmHg versus 6.6 ± 4 mmHg (p > 0.05) in the PMV and CSC groups, respectively. Mitral restenosis occurred in 5 (26.3%) patients in the PMV group versus 5 (27.8%) patients in the CSC group (p > 0.05). Kaplan-Meier curves for restenosis-free survival showed no difference between the 2 groups. Conclusion: PMV achieves comparable results to CSC both in the short and long term. © 2008 Japanese College of Cardiology.
Authors & Co-Authors
Rifaie, Osama A.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Dayem, M. Khairy A.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Ramzy, Aly
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Ezz-El-din, Hassan
Egypt, Cairo
Faculty of Medicine - Ain Shams University
El-Ziady, Galal
Egypt, Cairo
Faculty of Medicine - Ain Shams University
El Etriby, Adel K.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
El-Sayed, Hamdy
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Wagdy, Hassan
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Awadallah, Hany
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Nammas, Wail M.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Statistics
Citations: 34
Authors: 10
Affiliations: 1
Identifiers
Doi:
10.1016/j.jjcc.2008.08.003
ISSN:
09145087
Research Areas
Health System And Policy
Study Design
Cohort Study