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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Pantoea agglomerans bloodstream infection in preterm neonates
Medical Principles and Practice, Volume 17, No. 6, Year 2008
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Description
Objective: To report an uncommon incidence of sporadic bloodstream infection (BSI) caused by Pantoea agglomerans in preterm neonates. Case Presentation and Intervention: Fives cases of nosocomial BSI with P. agglomerans in preterm neonates (weight ≤1,500 g; age 8-17 days; gestational age 26-30 weeks) are presented. All cases were late onset neonatal sepsis (>7 days of age). Lethargy, skin mottling and bradycardia were often present. Although there was no evidence of pneumonia, desaturation was a common feature. Thrombocytopenia developed in 4 patients, metabolic acidosis in 2 and jaundice in 2. No bleeding tendency or disseminating intravascular coagulation was recorded. Organisms cultured from blood were identified by the Vitek-2 system (bioMérieux, France) and the findings confirmed by testing the isolate on the API 20E system. All isolates shared in vitro susceptibility to gentamicin, amikacin, ciprofloxacin, piperacillin/tazobactam and meropenem. One patient was treated with a cefotaxime/amikacin combination, 2 with meropenem and the remaining 2 with tazocin. All patients responded well to antibiotic treatment and survived. Conclusion:P. agglomerans is an unusual pathogen in the etiology of neonatal sepsis. Despite significant clinical deterioration, early detection and proper antibiotic therapy carry a favorable outcome. Copyright © 2008 S. Karger AG.
Authors & Co-Authors
Aly, Nasser Yehia A.
Egypt, Alexandria
Faculty of Medicine
Kuwait, Safat
Farwania Hospital
Salmeen, Hadeel N.
Kuwait
Al-sabah Hospital
Lila, Reda A.Abo
Kuwait, Safat
Farwania Hospital
Nagaraja, Prem A.
Kuwait, Safat
Farwania Hospital
Statistics
Citations: 47
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1159/000151575
ISSN:
10117571
Research Areas
Health System And Policy
Maternal And Child Health
Noncommunicable Diseases
Study Design
Randomised Control Trial
Cohort Study