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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Distribution of yeast species associated with oral lesions in HIV-infected patients in Southwest Uganda
Medical Mycology, Volume 50, No. 3, Year 2012
Notification
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Description
Oropharyngeal candidiasis remains a significant clinical problem in HIV-infected and AIDS patients in regions of Africa where anti-retroviral therapy isn't readily available. In this study we identified the yeast populations associated with oral lesions in HIV-infected patients in Southwest Uganda who were receiving treatment with nystatin and topical clotrimazole. Samples were taken from 605 patients and 316 (52%) of these yielded yeast growth following incubation on Sabouraud dextrose agar. Samples were subsequently re-plated on CHROMagar Candida medium to facilitate identification of the yeast species present. The majority (56%) of culture-positive samples yielded a mix of two or more species. Candida albicans was present in 87% (274/316) of patient samples and accounted for 87% (120/138) of single species samples. Candida glabrata, Candida tropicalis and Candida norvegensis were also found in cultures that yielded a single species. No Candida dubliniensis isolates were identified in this population. © 2012 ISHAM.
Authors & Co-Authors
Agwu, Ezera
Uganda, Kampala
Kampala International University
Ihongbe, John Cletus
Nigeria, Ekpoma
Ambrose Alli University
McManus, Brenda A.
Ireland, Dublin
Dublin Dental University Hospital
Moran, Gary P.
Ireland, Dublin
Dublin Dental University Hospital
Coleman, D. C.
Ireland, Dublin
Dublin Dental University Hospital
Sullivan, Derek J.
Ireland, Dublin
Dublin Dental University Hospital
Statistics
Citations: 26
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.3109/13693786.2011.604862
ISSN:
13693786
e-ISSN:
14602709
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Study Locations
Uganda