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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Two new jaspamide derivatives from the marine sponge Jaspis splendens
Marine Drugs, Volume 7, No. 3, Year 2009
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Description
Two new jaspamide derivatives 2 and 3, together with the parent compound jaspamide (1) have been isolated from the marine sponge Jaspis splendens collected in Kalimantan (Indonesia). The structures of the new compounds were unambiguously elucidated based on 1D and 2D NMR spectral data, mass spectrometry and comparison with jaspamide (1). The new derivatives inhibited the growth of mouse lymphoma (L5178Y) cell line in vitro with IC50 values of <0.1 μg/mL. © 2009 by the authors.
Authors & Co-Authors
S Ebada, Sherif Saeed
Germany, Dusseldorf
Heinrich-heine-universität Düsseldorf
Egypt, Cairo
Faculty of Pharmacy - Ain Shams University
Wray, Victor
Germany, Braunschweig
Helmholtz Centre for Infection Research Hzi
de Voogd, Nicole Joy D.E.
Netherlands, Leiden
Naturalis Biodiversity Center
Deng, Zhiwei
China, Beijing
Beijing Normal University
Lin, Wenhang Han
China, Beijing
Peking University
Proksch, Peter
Germany, Dusseldorf
Heinrich-heine-universität Düsseldorf
Statistics
Citations: 45
Authors: 6
Affiliations: 6
Identifiers
Doi:
10.3390/md7030435
e-ISSN:
16603397