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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Seroprevalence and clinico-epidemiological correlates of hepatitis C viral antibodies at an antenatal booking clinic of a tertiary hospital in Nigeria
Archives of Gynecology and Obstetrics, Volume 288, No. 3, Year 2013
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Description
Purpose: This was to determine the sero-prevalence of hepatitis C viral (HCV) antibodies in pregnant women attending the first antenatal clinic and assess the epidemiologic correlates of women anti-HCV positive. Methods: This was a prospective observational study which used in vitro diagnostic test kits to detect anti-HCV antibodies. Women attending their first antenatal clinic were recruited at the antenatal clinic of Irrua Specialist Teaching Hospital, Edo State, Nigeria. Seropositive women had liver enzymes assessed, and screening for hepatitis B surface antigen and Human Immuno-deficiency Virus (HIV) was done. Results: Eight out of 205 women were anti-HCV positive. The prevalence of hepatitis C infection was 3.9 %. The mean age of the women was 28.9 ± 2.1 years. Most (50 %) anti-HCV positive women had tertiary level education. Though health workers made up 3.5 % of the participants, they constituted 25 % women with anti-HCV antibody. Awareness of HCV infection had no impact on the rate of infection. Multiple sexual partners (P = 0.71), blood transfusion (0.64) and female circumcision (P = 1.00) were not significant risks of infection. 2 (1 %) women had hepatitis B co-infection and 1 (12.5 %) woman had both HCV antibody and HIV co-infection. Conclusion: Despite the 3.9 % prevalence, routine screening for hepatitis C virus infection in pregnancy is unjustified. Risk-based screening using locally prevailing risk factors with antenatal monitoring and postpartum treatment of women with hepatitis C antibodies is recommended. © 2013 Springer-Verlag Berlin Heidelberg.
Authors & Co-Authors
Okusanya, Babasola O.
Nigeria, Lagos
University of Lagos
Aigere, Egbaname Obozegie Samuel
Nigeria
Federal Medical Centre Nigeria
Eigbefoh, Joseph O.
Nigeria, Hamburg
Irrua Specialist Teaching Hospital
Ikheloa, Joseph
Nigeria, Hamburg
Irrua Specialist Teaching Hospital
Statistics
Citations: 12
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1007/s00404-013-2773-4
ISSN:
09320067
e-ISSN:
14320711
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Nigeria
Participants Gender
Female