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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)
African Journal of Biotechnology, Volume 6, No. 10, Year 2007
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Description
15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p<0.05). It was 81.5 ± 13.62 × 106/ml and 70 ± 12.98 × 106/ml in groups Band C, respectively, as compared to 59.8 ± 2.14 × 106/ml in the Control group. © 2007 Academic Journals.
Authors & Co-Authors
Oluyemi, Kayode Alaba
Nigeria, Benin
Igbinedion University Okada
Jimoh, Olusegun R.
Nigeria, Ilorin
University of Ilorin
Adesanya, Olamide A.
Nigeria, Benin
Igbinedion University Okada
Omotuyi, Olaposi I.
Nigeria, Benin
Igbinedion University Okada
Josiah, Sunday Joel
Nigeria, Benin
Igbinedion University Okada
Oyesola, Tolulope O.
Nigeria, Benin
Igbinedion University Okada
Statistics
Citations: 6
Authors: 6
Affiliations: 2
Identifiers
e-ISSN:
16845315
Research Areas
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Participants Gender
Male