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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
T cells activation and interferon-γ/nitric oxide production during behçet disease: A study in Algerian patients
Ocular Immunology and Inflammation, Volume 20, No. 3, Year 2012
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Description
The aim of the current study is to situate CDs expression (CD3+, CD4+, CD8+) and their relationship with IFNγ and NO production in Algerian patients with Behçet disease (n=34). Our results revealed an elevated expression of T cells markers tested in patients in active stage of the disease in relation to IFNγ and NO increase levels. Most interestingly, we noted that CD4+/CD8+ expression correlated with IFNγ and NO production in active stage. In contrast, we observed a decrease of these mediators in inactive stage. Collectively, our results indicate a dependent relation between these parameters and inflammatory response associated with the evolutionary stage of the disease. © 2012 Informa Healthcare USA, Inc.
Authors & Co-Authors
Djaballah-Ider, Fatmazohra
Algeria, Algiers
Université Des Sciences et de la Technologie Houari Boumediene
Chaib, Samia
Algeria, Algiers
Ain Naadja Hospital
Belguendouz, Houda
Algeria, Algiers
Université Des Sciences et de la Technologie Houari Boumediene
Talbi, Djameleddine
Algeria, Algiers
Ain Naadja Hospital
Touil-Boukoffa, Chafia
Algeria, Algiers
Université Des Sciences et de la Technologie Houari Boumediene
Statistics
Citations: 16
Authors: 5
Affiliations: 2
Identifiers
Doi:
10.3109/09273948.2012.671882
ISSN:
09273948
e-ISSN:
17445078
Research Areas
Health System And Policy