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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
HIV‐associated lymphoma in Africa: An autopsy study in Ĉote D'ivoire
International Journal of Cancer, Volume 59, No. 1, Year 1994
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Description
HIV infection predisposes to the development of non‐Hodgkin lymphoma (NHL). The frequency of NHL among HIV‐positive adults and children in sub‐Saharan Africa is not known. In 1991–1992, a representative autopsy study of HIV infection was performed in Abidjan, Cǒte d'Ivoire. Of 247 HIV‐positive adult (> 14 years) medical patients dying in hospital, 2.8% had NHL, 1.6% with visceral NHL and 1.2% with primary cerebral lymphoma. The estimated crude incidence of NHL among HIV‐positive adults in Abidjan was 84/ 100,000 per year, 10‐fold greater than the expected pre‐AIDS incidence of NHL but less than the incidence observed among HIV‐positive adults in industrialised countries. None of 78 autopsied HIV‐positive children (median age = 17 months) had NHL. HIV infection augments the incidence of NHL among adults in Africa, but short survival with advanced HIV disease probably prevents the major increase in HIV‐associated NHL seen in industrialised countries. Survival of HIV‐positive children in Africa appears too short to permit the significant development of additional NHL; classic Burkitt lymphoma is not an AIDS‐associated tumour in Africa. Copyright © 1994 Wiley‐Liss, Inc., A Wiley Company
Authors & Co-Authors
Lucas, Sebastian B.
United Kingdom, London
Ucl Medical School
Diomandé, Mohenou Isidore Jean Marie
Cote D'ivoire
University Hospitals
Hounnou, Anatole
Unknown Affiliation
Beaumel, A.
Cote D'ivoire
University Hospitals
Giordano, Christian
Cote D'ivoire
University Hospitals
Kadio, Auguste
Cote D'ivoire
University Hospitals
Peacock, Christopher S.
Unknown Affiliation
Hondé, Michel
Cote D'ivoire
University Hospitals
de Cock, Kevin M.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Statistics
Citations: 9
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1002/ijc.2910590106
ISSN:
00207136
e-ISSN:
10970215
Research Areas
Cancer
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cohort Study