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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Long-Term Follow-Up of Cerebral Aneurysms Completely Occluded at 6 Months After Intervention with the Woven EndoBridge (WEB) Device: a Retrospective Multicenter Observational Study
Translational Stroke Research, Year 2023
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Description
The Woven EndoBridge (WEB) device has been widely used to treat intracranial wide neck bifurcation aneurysms. Initial studies have demonstrated that approximately 90% of patients have same or improved long-term aneurysm occlusion after the initial 6-month follow up. The aim of this study is to assess the long-term follow-up in aneurysms that have achieved complete occlusion at 6 months. We also compared the predictive value of different imaging modalities used. This is an analysis of a prospectively maintained database across 13 academic institutions. We included patients with previously untreated cerebral aneurysms embolized using the WEB device who achieved complete occlusion at first follow-up and had available long-term follow-up. A total of 95 patients with a mean age of 61.6 ± 11.9 years were studied. The mean neck diameter and height were 3.9 ± 1.3 mm and 6.0 ± 1.8 mm, respectively. The mean time to first and last follow-up was 5.4 ± 1.8 and 14.1 ± 12.9 months, respectively. Out of all the aneurysms that were completely occluded at 6 months, 84 (90.3%) showed complete occlusion at the final follow-up, and 11(11.5%) patients did not achieve complete occlusion. The positive predictive value (PPV) of complete occlusion at first follow was 88.4%. Importantly, this did not differ between digital subtraction angiography (DSA), magnetic resonance angiography (MRA), or computed tomography angiography (CTA). This study underlines the importance of repeat imaging in patients treated with the WEB device even if complete occlusion is achieved short term. Follow-up can be performed using DSA, MRA or CTA with no difference in positive predictive value. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Authors & Co-Authors
El Naamani, Kareem
United States, Philadelphia
Thomas Jefferson University Hospital
Mastorakos, Panagiotis
United States, Philadelphia
Thomas Jefferson University Hospital
Lan, Matthews
United States, Philadelphia
Thomas Jefferson University Hospital
Khanna, Omaditya
United States, Philadelphia
Thomas Jefferson University Hospital
Diestro, Jose Danilo Bengzon
Canada, Toronto
University of Toronto
McLellan, Rachel M.
United States, Boston
Brigham and Women's Hospital
Dibas, Mahmoud
Canada, Toronto
University of Toronto
United States, Boston
Brigham and Women's Hospital
Vranic, Justin E.
United States, Boston
Brigham and Women's Hospital
Carnevale, Joseph A.
United States, New York
Weill Cornell Medicine
Saliou, Guillaume
Switzerland, Lausanne
Centre Hospitalier Universitaire Vaudois
Möhlenbruch, Markus Alfred
Germany, Heidelberg
Universitätsklinikum Heidelberg
Waqas, Muhammad
United States, Buffalo
University at Buffalo, the State University of new York
Tutino, Vincent Matthew
United States, Buffalo
University at Buffalo, the State University of new York
Rabinov, James David
United States, Boston
Brigham and Women's Hospital
Spears, Julian
Canada, Toronto
University of Toronto
Panni, Pietro
Italy, Milan
Irccs Ospedale San Raffaele
Griessenauer, Christoph Johannes
Austria, Salzburg
Paracelsus Medizinische Privatuniversitat
Asadi, Hamed
Australia, Melbourne
Austin Health
Regenhardt, Robert W.
United States, Boston
Brigham and Women's Hospital
Stapleton, Christopher J.
United States, Boston
Brigham and Women's Hospital
Ghozy, Sherief A.
United States, Boston
Brigham and Women's Hospital
Siddiqui, Adnan Hussain
United States, Buffalo
University at Buffalo, the State University of new York
Kan, Peter Tze Man
United States, Houston
Baylor College of Medicine
Ali Aziz-Sultan, Mohammad Ali
United States, Boston
Brigham and Women's Hospital
Abbas, Rawad
United States, Philadelphia
Thomas Jefferson University Hospital
Amllay, Abdelaziz
United States, Philadelphia
Thomas Jefferson University Hospital
Tjoumakaris, Stavropoula I.
United States, Philadelphia
Thomas Jefferson University Hospital
Gooch, Michael Reid
United States, Philadelphia
Thomas Jefferson University Hospital
Herial, N. A.
United States, Philadelphia
Thomas Jefferson University Hospital
Rosenwasser, Robert H.
United States, Philadelphia
Thomas Jefferson University Hospital
Mendes Pereira, Vitor Mendes D.
Canada, Toronto
University of Toronto
Patel, Aman B.
United States, Boston
Brigham and Women's Hospital
Jabbour, P. M.
United States, Philadelphia
Thomas Jefferson University Hospital
Dmytriw, Adam Andrew
Canada, Toronto
University of Toronto
United States, Boston
Brigham and Women's Hospital
Statistics
Authors: 34
Affiliations: 15
Identifiers
Doi:
10.1007/s12975-023-01153-5
ISSN:
18684483
Study Design
Randomised Control Trial
Cohort Study