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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cyclosporin A in the treatment of severe acute aplastic anaemia
British Journal of Haematology, Volume 61, No. 2, Year 1985
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Description
Summary. Twelve consecutive adults with severe acute aplastic anaemia, not having a bone marrow transplantation option, were prospectively randomized to receive either cyclosporin A alone or an equivalent amount of this immunosuppressive agent in combination with antilymphocyte serum. The minimum follow‐up is 36 months, with half the patients developing nephrotoxicity, which was easily reversible in all but one. No response could be attributed to either regimen. Cyclosporin A does not appear to have a place as primary form of treatment for adults with severe acute aplastic anaemia, either on its own or in combination with antilymphocyte serum. Copyright © 1985, Wiley Blackwell. All rights reserved
Authors & Co-Authors
Jacobs, Peter B.
South Africa, Observatory
Groote Schuur Hospital
Wood, Lucille
South Africa, Observatory
Groote Schuur Hospital
Martell, Robert W.
South Africa, Observatory
Groote Schuur Hospital
Statistics
Citations: 30
Authors: 3
Affiliations: 1
Identifiers
Doi:
10.1111/j.1365-2141.1985.tb02825.x
ISSN:
00071048
e-ISSN:
13652141