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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Pandemic (H1N1) 2009 influenza in the UK: Clinical and epidemiological findings from the first few hundred (FF100) cases
Epidemiology and Infection, Volume 138, No. 11, Year 2010
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Description
The UK was one of few European countries to document a substantial wave of pandemic (H1N1) 2009 influenza in summer 2009. The First Few Hundred (FF100) project ran from April-June 2009 gathering information on early laboratory-confirmed cases across the UK. In total, 392 confirmed cases were followed up. Children were predominantly affected (median age 15 years, IQR 10-27). Symptoms were mild and similar to seasonal influenza, with the exception of diarrhoea, which was reported by 27%. Eleven per cent of all cases had an underlying medical condition, similar to the general population. The majority (92%) were treated with antiviral drugs with 12% reporting adverse effects, mainly nausea and other gastrointestinal complaints. Duration of illness was significantly shorter when antivirals were given within 48 h of onset (median 5 vs. 9 days, P=001). No patients died, although 14 were hospitalized, of whom three required mechanical ventilation. The FF100 identified key clinical and epidemiological characteristics of infection with this novel virus in near real-time. Copyright © 2010 Cambridge University Press.
Authors & Co-Authors
McLean, Estelle M.
United Kingdom, London
Public Health England
Pebody, Richard G.
United Kingdom, London
Public Health England
Campbell, Colin N.J.
United Kingdom, London
Public Health England
Chamberland, Mary E.
United Kingdom, London
Public Health England
Nguyen-Van-Tam, Jonathan S.
United Kingdom, Nottingham
University of Nottingham
Oliver, Isabel
United Kingdom, London
Public Health England
Smith, Gillian Elizabeth
United Kingdom, London
Public Health England
Ihekweazu, Chikwe A.
United Kingdom, London
Public Health England
Bracebridge, Samantha
United Kingdom, London
Public Health England
Maguire, Helen C.F.
United Kingdom, London
Public Health England
Harris, Ross Jeremy
United Kingdom, London
Public Health England
Kafatos, George
United Kingdom, London
Public Health England
White, Peter J.
United Kingdom, London
Public Health England
United Kingdom, London
Medical Research Council
Green, Jonathan
United Kingdom, London
Public Health England
Myers, Richard E.
United Kingdom, London
Public Health England
Underwood, Anthony P.
United Kingdom, London
Public Health England
Dallman, Timothy James
United Kingdom, London
Public Health England
Zambon, Maria C.
United Kingdom, London
Public Health England
Ellis, Joanna S.
United Kingdom, London
Public Health England
Phin, Nicholas Fulton
United Kingdom, London
Public Health England
Smyth, Brian
United Kingdom, Belfast
Public Health Agency
Statistics
Citations: 67
Authors: 21
Affiliations: 5
Identifiers
Doi:
10.1017/S0950268810001366
ISSN:
14694409
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study